SCHEMBL316664

SCHEMBL316664

Cc1cn([C@H]2CC(O)[C@@H](CON)O2)c(=O)[nH]c1=O

nearest known ligand 0.70

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.67
TK1 P04183 4/20 0.64
TYMS P04818 1/20 0.59
BCHE P06276 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL646741 1.00 POLB (0.67) POLBTK1TYMSBCHE
SCHEMBL6753328 0.90 POLB (0.61) POLBTK1TYMS
SCHEMBL17236294 0.89 TK1 (0.69) POLBTK1TYMSBCHE
SCHEMBL22943603 0.89 TK1 (0.69) POLBTK1TYMSBCHE
SCHEMBL4198253 0.89 TK1 (0.69) POLBTK1TYMSBCHE
SCHEMBL12918450 0.89 TK1 (0.69) POLBTK1TYMSBCHE
SCHEMBL17232081 0.89 TK1 (0.69) POLBTK1TYMSBCHE
SCHEMBL135209 0.89 TK1 (0.69) POLBTK1TYMSBCHE
SCHEMBL6379335 0.89 POLB (0.68) POLBTK1TYMSBCHE
SCHEMBL4809523 0.89 POLB (0.68) POLBTK1TYMSBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117343990-A Method and kit for determining target polynucleotide and probe set 牛津纳米孔科技公开有限公司 2024-01-05 CN disclosed
CN-112703256-A Method for determining polymer sequence 牛津纳米孔科技公司 2021-04-23 CN disclosed
CN-112074611-A Method and polynucleotide for amplifying target polynucleotide 牛津纳米孔科技公司 2020-12-11 CN disclosed
CN-106232834-B Sample preparation method 牛津纳米孔技术公司 2020-09-22 CN disclosed
US-20170266284-A1 PERSONALIZED METHODS FOR TREATING DISEASE BY RADIOSENSITIZATION KINSELLA TIMOTHY J (US) 2017-09-21 US disclosed
US-9410189-B2 Methods of preventing non-specific reactions of nucleotide sequences CO-DIAGNOSTICS, INC. (US) 2016-08-09 US disclosed
WO-2016044690-A1 PERSONALIZED METHODS FOR TREATING DISEASE BY RADIOSENSITIZATION SHUTTLE PHARMACEUTICALS, LLC (US) 2016-03-24 WO disclosed
US-9034798-B2 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions CAPROTEC BIOANALYTICS GMBH (DE) 2015-05-19 US disclosed
EP-2770058-A1 Ligand and method for detection of okadaic acid Université de Perpignan (FR) 2014-08-27 EP disclosed
US-8569481-B2 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions PHARMACEUTICALS, INC. (US) 2013-10-29 US disclosed
WO-2001057523-A1 STRUCTURE IDENTIFICATION METHODS USING MASS MEASUREMENTS NANOSCALE COMBINATORIAL SYNTHESIS, INC. (US) 2001-08-09 WO disclosed
US-6200748-B1 OLIGONUCLEOTIDE SEQUENCES AND A TEMPLATE; FOR MONITORING AND DETECTING NUCLEOTIDE SEQUENCES; FOR THE ANALYSIS OF NUCLEIC ACIDS CALIFORNIA INSTITUTE OF TECHNOLOGY 2001-03-13 US disclosed
US-5821058-A SEPARATING PLURALITY OF POLYNUCLEOTIDES, EACH TAGGED WITH CHROMOPHORE OR FLUOROPHORE, BY ELECTROPHORESIS, DETECTING CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1998-10-13 US disclosed
US-5552540-A NONRADIOACTIVE LABELS HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE (AU) 1996-09-03 US disclosed
EP-0366685-B1 NUCLEOSIDE DERIVATIVES FLOREY HOWARD INST (AU) 1994-10-19 EP disclosed
US-5171534-A Electrophoretic analysis of DNA fragments tagged with fluorophore; absorption or fluorescent photometer CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1992-12-15 US disclosed
EP-0366685-A4 NUCLEOSIDE DERIVATIVES 1991-03-20 EP disclosed
EP-0366685-A1 NUCLEOSIDE DERIVATIVES. FLOREY HOWARD INST (AU) 1990-05-09 EP disclosed
WO-1988010264-A1 NUCLEOSIDE DERIVATIVES HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY (AU) 1988-12-29 WO disclosed
US-3791928-A PURIFICATION OF THYMIDINE KINASE MAX PLANCK GESELLSCHAFT 1974-02-12 US disclosed