SCHEMBL135209

SCHEMBL135209

COC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)C[C@@H]1O

nearest known ligand 0.72

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TK1 P04183 3/20 0.69
POLB P06746 1/20 0.68
TYMS P04818 1/20 0.60
BCHE P06276 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22943603 1.00 TK1 (0.69) TK1POLBTYMSBCHE
SCHEMBL17236294 1.00 TK1 (0.69) TK1POLBTYMSBCHE
SCHEMBL4198253 1.00 TK1 (0.69) TK1POLBTYMSBCHE
SCHEMBL522285 1.00 TK1 (0.69) TK1POLBTYMSBCHE
SCHEMBL17232081 1.00 TK1 (0.69) TK1POLBTYMSBCHE
SCHEMBL12918450 1.00 TK1 (0.69) TK1POLBTYMSBCHE
SCHEMBL8470853 0.91 TK1 (0.64) TK1POLBTYMSBCHE
SCHEMBL7571044 0.91 TK1 (0.66) TK1POLBTYMSBCHE
SCHEMBL4804983 0.91 POLB (0.68) TK1POLBTYMSBCHE
SCHEMBL6379335 0.91 POLB (0.68) TK1POLBTYMSBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 737 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118043078-A SIRP-alpha antibodies and conjugates 塔拉克治疗公司 2024-05-14 CN claimed
CN-117836413-A Connexin-4 antibodies and conjugates 塔拉克治疗公司 2024-04-05 CN claimed
EP-4110365-A2 FIDGETIN-LIKE 2 AS A TARGET TO ENHANCE WOUND HEALING Microcures, Inc. (US) 2023-01-04 EP claimed
CN-115427458-A Transglutaminase mediated conjugation 塔拉克治疗公司 2022-12-02 CN claimed
WO-2019195494-A1 COMPOSITIONS AND METHODS FOR SYNTHESIS OF PHOSPHORYLATED MOLECULES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-10-10 WO claimed
CN-105596356-A Compositions and methods for combination antiviral therapy GILEAD SCIENCES INC 2016-05-25 CN claimed
US-9249173-B2 Compounds and pharmaceutical compositions for the treatment of viral infections IDENIX PHARMACEUTICALS, LLC (US) 2016-02-02 US claimed
EP-0767842-B1 METHODS OF SCREENING FOR NUCLEOSIDE ANALOGS THAT ARE INCORPORATED BY HIV REVERSE TRANSCRIPTASE AND CAUSE INCORRECT BASE PAIRING UNIV WASHINGTON (US) 2000-09-27 EP claimed
EP-1004675-A2 Methods of screening for nucleoside analogs that are incorporated by HIV reverse transcriptase and cause incorrect base pairing DARWIN MOLECULAR CORPORATION (US) 2000-05-31 EP claimed
EP-0767842-A1 METHODS OF SCREENING FOR NUCLEOSIDE ANALOGS THAT ARE INCORPORATED BY HIV REVERSE TRANSCRIPTASE AND CAUSE INCORRECT BASE PAIRING DARWIN MOLECULAR CORPORATION (US) 1997-04-16 EP claimed
WO-1996000797-A1 METHODS OF SCREENING FOR NUCLEOSIDE ANALOGS THAT ARE INCORPORATED BY HIV REVERSE TRANSCRIPTASE AND CAUSE INCORRECT BASE PAIRING DARWIN MOLECULAR CORP (US) 1996-01-11 WO claimed
US-12584168-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-03-24 US disclosed
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS OPENTRONS LABWORKS INC (US) 2026-03-05 US disclosed
US-12527846-B2 Immunodominant proteins and fragments in multiple sclerosis Universität Zürich (CH) 2026-01-20 US disclosed
US-20250345413-A1 SARS-COV-2 SUBUNIT VACCINE Viravaxx AG (AT) 2025-11-13 US disclosed
US-4444776-A ANTITUMOR, ANTIVIRAL AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (A N V A R) (FR) 1984-04-24 US disclosed
EP-0099133-A2 Anti-cancer drugs comprising platinum complexes YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD. (IL) 1984-01-25 EP disclosed
US-4377514-A HOMOGENIZING, ACIDIFYING, DENATURING, AND CENTRIFUGING INTESTINAL LYMPH GLANDS; HORMONES MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) 1983-03-22 US disclosed
US-4266060-A ANTITUMOR ANTIVIRAL AGENTS FOR TREATMENT OF CANCER AGENCE NATIONALE DE VAL ORISATION DE LA RECHERCHE (ANVAR) (FR) 1981-05-05 US disclosed
US-4064007-A ANTITUMOR AGENTS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 1977-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584168-B2 Sample preparation method POLN, POLRMT, POLM TK1 472/4885POLB 4/4885TYMS 273/4885
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS POLRMT, POLL, SARS1 TK1 1713/4885POLB 12/4885TYMS 179/4885
US-12527846-B2 Immunodominant proteins and fragments in multiple sclerosis MAG, GMFG, FUCA1 TK1 3147/4885POLB 4725/4885TYMS 1943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.