Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | TK1 | P04183 | 4/20 | 0.64 |
| ▸ | TYMS | P04818 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316664 | 1.00 | POLB (0.67) | POLBTK1TYMSBCHE | |
| SCHEMBL6753328 | 0.90 | POLB (0.61) | POLBTK1TYMS | |
| SCHEMBL17236294 | 0.89 | TK1 (0.69) | POLBTK1TYMSBCHE | |
| SCHEMBL22943603 | 0.89 | TK1 (0.69) | POLBTK1TYMSBCHE | |
| SCHEMBL4198253 | 0.89 | TK1 (0.69) | POLBTK1TYMSBCHE | |
| SCHEMBL12918450 | 0.89 | TK1 (0.69) | POLBTK1TYMSBCHE | |
| SCHEMBL17232081 | 0.89 | TK1 (0.69) | POLBTK1TYMSBCHE | |
| SCHEMBL135209 | 0.89 | TK1 (0.69) | POLBTK1TYMSBCHE | |
| SCHEMBL6379335 | 0.89 | POLB (0.68) | POLBTK1TYMSBCHE | |
| SCHEMBL4809523 | 0.89 | POLB (0.68) | POLBTK1TYMSBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 435 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110819604-B | Deoxyribotransferase mutant and application thereof | 上海兆维科技发展有限公司 | 2021-07-27 | — | — | CN | claimed |
| CN-110819604-A | Deoxyribotransferase mutant and application thereof | 上海兆维科技发展有限公司 | 2020-02-21 | — | — | CN | claimed |
| EP-3458081-B1 | POLYNUCLEOTIDES ENCODING CITRIN FOR THE TREATMENT OF CITRULLINEMIA TYPE 2 | MODERNATX INC (US) | 2026-04-15 | — | — | EP | disclosed |
| EP-4709417-A2 | POLYNUCLEOTIDES ENCODING NOROVIRUS VP1 ANTIGENS AND USES THEREOF | Merck Sharp & Dohme LLC (US) | 2026-03-18 | — | — | EP | disclosed |
| EP-3887519-B1 | METHODS OF DETERMINING PH AND CALCIUM OR CHLORIDE CONCENTRATION IN SAMPLES | UNIV CHICAGO (US) | 2025-11-05 | — | — | EP | disclosed |
| US-12436156-B2 | Methods of determining pH and calcium or chloride concentration in samples | THE UNIVERSITY OF CHICAGO (US) | 2025-10-07 | — | — | US | disclosed |
| WO-2025111430-A1 | CHEMICAL MODIFICATIONS IN mRNA POLY(A) TAIL | PRIME MEDICINE, INC. (US) | 2025-05-30 | — | — | WO | disclosed |
| US-20250122499-A1 | ARTIFICIAL NUCLEIC ACIDS FOR RNA EDITING | EBERHARD KARLS UNIVERSITÄT TÜBINGEN (DE) | 2025-04-17 | — | — | US | disclosed |
| US-12276654-B2 | Chemical probe-dependent evaluation of protein activity and uses thereof | THE UNIVERSITY OF CHICAGO (US) | 2025-04-15 | — | — | US | disclosed |
| US-20240426847-A1 | COMPOSITIONS AND METHODS FOR THE DETERMINATION OF SODIUM CONCENTRATION | THE UNIVERSITY OF CHICAGO | 2024-12-26 | — | — | US | disclosed |
| US-20240385200-A1 | COMPOSITIONS AND METHODS OF DETERMINING PH AND POTASSIUM CONCENTRATION IN SAMPLES | THE UNIVERSITY OF CHICAGO | 2024-11-21 | — | — | US | disclosed |
| WO-1992005186-A1 | MODIFIED INTERNUCLEOSIDE LINKAGES | GILEAD SCIENCES (US) | 1992-04-02 | — | — | WO | disclosed |
| WO-1992002534-A2 | COMPOUNDS AND METHODS FOR INHIBITING GENE EXPRESSION | STERLING DRUG, INC. (US) | 1992-02-20 | — | — | WO | disclosed |
| WO-1992002638-A1 | HOMOGENEOUS ASSAY SYSTEM | F. HOFFMANN-LA ROCHE AG (CH) | 1992-02-20 | — | — | WO | disclosed |
| US-5015733-A | Phosphoramidites and oligonucleotides derived therefrom | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1991-05-14 | — | — | US | disclosed |
| US-4988617-A | DNA OR RNA SEQUENCE DETERMINATION FOR POSSIBLE MUTANTS, ANNEALING A TARGET NUCLEOTIDE, CROSSLINKING, DETECTION | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1991-01-29 | — | — | US | disclosed |
| US-4849513-A | Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1989-07-18 | — | — | US | disclosed |
| EP-0258412-A1 | COMPOSITION FOR AND METHOD OF TREATING AIDS AND CERTAIN RELATED DISEASES | GREER, Sheldon B. (US) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987004929-A1 | COMPOSITION FOR AND METHOD OF TREATING AIDS AND CERTAIN RELATED DISEASES | GREER SHELDON B | 1987-08-27 | — | — | WO | disclosed |
| US-4210638-A | 5-TRIFLUOROMETHYL-2'-DEOXYCYCTIDINE AND TETRAHYDROURIDINE OR 2'-DEOXYTETRAHYDROURIDINE | PCR, INC. (US) | 1980-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12276654-B2 | Chemical probe-dependent evaluation of protein activity and uses thereof | GBA3, ACP1, GUSB | POLB 3109/4885TK1 67/4885TYMS 3173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.