SCHEMBL31667119

SCHEMBL31667119

O=C1c2ccccc2C(Cc2ncccc2Cl)N1Cc1ccc2[nH]c(=O)oc2c1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ IL4I1 Q96RQ9 1/20 0.37
▸ PRMT5 O14744 1/20 0.36
▸ WDR77 Q9BQA1 1/20 0.36
▸ MAPK1 P28482 2/20 0.36
▸ ALDH1A1 P00352 3/20 0.36
▸ MEN1 O00255 2/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ LMNA P02545 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ GAA P10253 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.35
▸ MDM2 Q00987 3/20 0.34
▸ HPGD P15428 1/20 0.34
▸ SYK P43405 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31667213 0.90 PRMT5 (0.40) IL4I1PRMT5WDR77MAPK1ALDH1A1
SCHEMBL31667623 0.90 IL4I1 (0.39) IL4I1PRMT5WDR77MAPK1ALDH1A1
SCHEMBL31667444 0.90 IL4I1 (0.37) IL4I1PRMT5WDR77MAPK1ALDH1A1
SCHEMBL31667004 0.90 IL4I1 (0.37) IL4I1PRMT5WDR77MAPK1ALDH1A1
SCHEMBL31667349 0.90 IL4I1 (0.39) IL4I1PRMT5WDR77MAPK1ALDH1A1
SCHEMBL31667612 0.90 IL4I1 (0.39) IL4I1PRMT5WDR77MAPK1ALDH1A1
SCHEMBL31667648 0.90 IL4I1 (0.37) IL4I1PRMT5WDR77MAPK1ALDH1A1
SCHEMBL31667030 0.89 IL4I1 (0.36) IL4I1PRMT5WDR77MAPK1ALDH1A1
SCHEMBL31667157 0.89 IL4I1 (0.39) IL4I1PRMT5WDR77MAPK1ALDH1A1
SCHEMBL31667402 0.89 ATXN2 (0.39) IL4I1PRMT5WDR77MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078130-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF SIRONAX LTD (KY) 2026-03-19 — — US disclosed
EP-4590674-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF Sironax Ltd (KY) 2025-07-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078130-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF NAMPT, NNMT, SARM1 IL4I1 2872/4885PRMT5 981/4885WDR77 2686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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