SCHEMBL31667398

SCHEMBL31667398

COc1ccc(-c2noc(N3CCN(C(=O)NCCCN4CCN(Cc5ccccn5)CC4)CC3)n2)cc1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 5/20 0.55
▸ MAPT P10636 5/20 0.55
▸ HTT P42858 4/20 0.55
▸ SMN1; SMN2 Q16637 4/20 0.55
▸ TP53 P04637 4/20 0.55
▸ KDM4E B2RXH2 2/20 0.55
▸ ALDH1A1 P00352 2/20 0.55
▸ HSD17B10 Q99714 1/20 0.55
▸ MEN1 O00255 1/20 0.54
▸ KMT2A Q03164 1/20 0.54
▸ GAA P10253 2/20 0.54
▸ NPC1 O15118 1/20 0.53
▸ POLB P06746 1/20 0.51
▸ HTR1A P08908 2/20 0.49
▸ HTR7 P34969 2/20 0.49
▸ TSHR P16473 3/20 0.49
▸ THRB P10828 1/20 0.48
▸ GSK3B P49841 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL30584825 0.97 LMNA (0.52) LMNAMAPTHTTSMN1; SMN2TP53
SCHEMBL31667543 0.90 LMNA (0.58) LMNAMAPTHTTSMN1; SMN2TP53
SCHEMBL31667734 0.88 LMNA (0.51) LMNAMAPTHTTSMN1; SMN2TP53
SCHEMBL30584857 0.88 MAPT (0.57) LMNAMAPTHTTSMN1; SMN2TP53
Formic Acid SCHEMBL31546410 0.87 LMNA (0.56) LMNAMAPTHTTSMN1; SMN2TP53
Formic Acid SCHEMBL31546376 0.86 LMNA (0.49) LMNAMAPTHTTSMN1; SMN2TP53
SCHEMBL30584958 0.85 MAPT (0.52) LMNAMAPTHTTSMN1; SMN2TP53
SCHEMBL31546418 0.81 LMNA (0.72) LMNAMAPTHTTSMN1; SMN2TP53
SCHEMBL30584805 0.80 LMNA (0.48) LMNAMAPTHTTSMN1; SMN2TP53
SCHEMBL30584775 0.80 LMNA (0.49) LMNAMAPTHTTSMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP claimed
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
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