Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | HTT | P42858 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 3/20 | 0.49 |
| ▸ | SNCA | P37840 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8685114 | 0.87 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL6192299 | 0.87 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL8394619 | 0.87 | APP (0.63) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL8685326 | 0.86 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL8686724 | 0.86 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL8685269 | 0.86 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL8685588 | 0.85 | GCGR (0.54) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL8685733 | 0.85 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL8685406 | 0.83 | APP (0.49) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL13557315 | 0.82 | POLB (0.51) | ALDH1A1SMN1; SMN2HTTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250243160-A1 | INDOLE DERIVATIVES FOR TARGETING AUTOPHAGY | Automera PTE. LTD (SG) | 2025-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250243160-A1 | INDOLE DERIVATIVES FOR TARGETING AUTOPHAGY | SQSTM1, ATG7, BECN1 | ALDH1A1 3383/4885SMN1; SMN2 1199/4885HTT 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.