Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31669414 | 0.87 | RAB9A (0.50) | RAB9AL3MBTL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL31669155 | 0.82 | TP53 (0.44) | RAB9ASMN1; SMN2ALDH1A1GAANPC1 | |
| SCHEMBL31669152 | 0.82 | TP53 (0.44) | RAB9AKMT2ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL31669191 | 0.82 | EPHX1 (0.46) | RAB9AKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL31669375 | 0.81 | GAA (0.41) | RAB9AL3MBTL1SMN1; SMN2GAANPC1 | |
| SCHEMBL31669183 | 0.80 | KDM4E (0.54) | L3MBTL1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL31669098 | 0.79 | SMN1; SMN2 (0.41) | RAB9AL3MBTL1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL31669103 | 0.79 | TP53 (0.42) | KMT2AMEN1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL20887175 | 0.77 | SMN1; SMN2 (0.79) | RAB9AL3MBTL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL31669154 | 0.77 | GAA (0.63) | RAB9AKMT2AMEN1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12378224-B2 | Heteroaryl compounds and their use as Mer inhibitors | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2025-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12378224-B2 | Heteroaryl compounds and their use as Mer inhibitors | MERTK, RET, ERBB2 | RAB9A 1364/4885L3MBTL1 1353/4885KMT2A 2442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.