Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | F12 | P00748 | 1/20 | 0.41 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.41 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 5/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31669155 | 0.82 | TP53 (0.44) | TP53ALDH1A1HSD11B1KDM1AGAA | |
| SCHEMBL31669152 | 0.82 | TP53 (0.44) | TP53ALDH1A1KDM1AKMT2AGAA | |
| SCHEMBL26111986 | 0.80 | SMN1; SMN2 (0.59) | TP53ALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL31669378 | 0.79 | RAB9A (0.52) | TP53ALDH1A1F12MEN1KMT2A | |
| SCHEMBL31669191 | 0.79 | EPHX1 (0.46) | TP53ALDH1A1KDM1AMEN1KMT2A | |
| SCHEMBL20400631 | 0.78 | F12 (0.38) | TP53ALDH1A1HSD11B1MGLLF12 | |
| SCHEMBL31669154 | 0.77 | GAA (0.63) | TP53ALDH1A1MGLLKDM1AMEN1 | |
| SCHEMBL31669333 | 0.77 | SLC6A3 (0.51) | TP53ALDH1A1KDM1AMEN1KMT2A | |
| SCHEMBL31669098 | 0.76 | SMN1; SMN2 (0.41) | TP53ALDH1A1KDM1AKMT2AGAA | |
| SCHEMBL31669389 | 0.76 | SLC6A4 (0.41) | TP53KDM1AGAAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12378224-B2 | Heteroaryl compounds and their use as Mer inhibitors | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2025-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12378224-B2 | Heteroaryl compounds and their use as Mer inhibitors | MERTK, RET, ERBB2 | TP53 816/4885ALDH1A1 3864/4885HSD11B1 1828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.