Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31669389 | 0.86 | SLC6A4 (0.41) | GAATP53KDM1AMAOATSHR | |
| SCHEMBL31669155 | 0.82 | TP53 (0.44) | GAAALDH1A1SMN1; SMN2TP53KDM1A | |
| SCHEMBL31669152 | 0.82 | TP53 (0.44) | GAAALDH1A1SMN1; SMN2TP53KDM1A | |
| SCHEMBL31669378 | 0.82 | RAB9A (0.52) | GAAALDH1A1SMN1; SMN2TP53MEN1 | |
| SCHEMBL31669098 | 0.79 | SMN1; SMN2 (0.41) | GAAALDH1A1SMN1; SMN2TP53KDM1A | |
| SCHEMBL31669103 | 0.79 | TP53 (0.42) | GAAALDH1A1SMN1; SMN2TP53KDM1A | |
| SCHEMBL31669146 | 0.79 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2TP53KDM1AMAOA | |
| SCHEMBL31669154 | 0.77 | GAA (0.63) | GAAALDH1A1SMN1; SMN2TP53KDM1A | |
| SCHEMBL31669414 | 0.77 | RAB9A (0.50) | GAAALDH1A1SMN1; SMN2TP53KDM1A | |
| SCHEMBL31669333 | 0.77 | SLC6A3 (0.51) | GAAALDH1A1SMN1; SMN2TP53KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12378224-B2 | Heteroaryl compounds and their use as Mer inhibitors | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2025-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12378224-B2 | Heteroaryl compounds and their use as Mer inhibitors | MERTK, RET, ERBB2 | EPHX1 2304/4885GAA 1225/4885ALDH1A1 3864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.