Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 6/20 | 0.59 |
| ▸ | CHRM3 known ✓ | P20309 | 6/20 | 0.59 |
| ▸ | CHRM2 known ✓ | P08172 | 5/20 | 0.57 |
| ▸ | ACHE known ✓ | P22303 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.79 |
| ▸ | BLM | P54132 | 1/20 | 0.79 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.75 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.75 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.59 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.56 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290052 | 0.98 | ADRA2A (0.78) | MAPTBLMADRA2AADRA1ACHRM5 | |
| Hydrochloric Acid SCHEMBL19025642 | 0.96 | ADRA2A (0.75) | MAPTBLMADRA2AADRA1ACHRM5 | |
| Water SCHEMBL15994023 | 0.96 | ADRA2A (0.75) | MAPTBLMADRA2AADRA1ACHRM5 | |
| Fluoride Ion SCHEMBL15993972 | 0.96 | ADRA2A (0.75) | MAPTBLMADRA2AADRA1ACHRM5 | |
| Iodide SCHEMBL1157377 | 0.96 | ADRA2A (0.75) | MAPTBLMADRA2AADRA1ACHRM5 | |
| Bromide SCHEMBL8614700 | 0.96 | ADRA2A (0.75) | MAPTBLMADRA2AADRA1ACHRM5 | |
| SCHEMBL30511986 | 0.96 | ADRA2A (0.75) | MAPTBLMADRA2AADRA1ACHRM5 | |
| Bicarbonate SCHEMBL15993908 | 0.90 | ADRA2A (0.67) | MAPTBLMADRA2AADRA1ACHRM5 | |
| Suxamethonium SCHEMBL41536 | 0.89 | MAPT (1.00) | MAPTBLMADRA2AADRA1ACHRM5 | |
| Hydrochloric Acid SCHEMBL17910037 | 0.88 | MAPT (0.73) | MAPTBLMADRA2AADRA1ACHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111150849-A | Composition and preparation method and application thereof | 广州隽沐生物科技股份有限公司 | 2020-05-15 | — | — | CN | claimed |
| US-20100035997-A1 | KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES | BROADLEY KENNETH N | 2010-02-11 | — | — | US | claimed |
| EP-1317294-B2 | ABSORBABLE ADHESIVE COMPOSITIONS | CLOSURE MEDICAL CORP (US) | 2009-09-02 | — | — | EP | claimed |
| EP-1317294-B1 | ABSORBABLE ADHESIVE COMPOSITIONS | CLOSURE MEDICAL CORP (US) | 2005-03-16 | — | — | EP | claimed |
| EP-1355611-A2 | BRONCHIAL OCCLUSION METHOD AND APPARATUS | Closure Medical Corporation (US) | 2003-10-29 | — | — | EP | claimed |
| US-6620846-B1 | Containing biocompatible alkyl ester cyanoacrylate monomer and quaternary amine polymerization initiator | CLOSURE MEDICAL CORPORATION | 2003-09-16 | — | — | US | claimed |
| EP-1317294-A1 | ABSORBABLE ADHESIVE COMPOSITIONS | Closure Medical Corporation (US) | 2003-06-11 | — | — | EP | claimed |
| US-20020147462-A1 | Bronchial occlusion method and apparatus | CLOSURE MEDICAL CORPORATION | 2002-10-10 | — | — | US | claimed |
| WO-2002022072-A2 | BRONCHIAL OCCLUSION METHOD AND APPARATUS | CLOSURE MEDICAL CORPORATION (US) | 2002-03-21 | — | — | WO | claimed |
| WO-2002009785-A1 | ABSORBABLE ADHESIVE COMPOSITIONS | CLOSURE MEDICAL CORPORATION (US) | 2002-02-07 | — | — | WO | claimed |
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| EP-0315782-B1 | Method for the production of proteins | THOMAE GMBH DR K (DE) | 1994-09-28 | — | — | EP | claimed |
| EP-0315782-A2 | Method for the production of proteins | Dr. Karl Thomae GmbH (DE) | 1989-05-17 | — | — | EP | claimed |
| JP-1231887-A | — | — | None | — | — | JP | disclosed |
| US-4745108-A | Heparin derivatives having decreased anti-Xa specificity | MIAMI UNIVERSITY | 1988-05-17 | — | — | US | disclosed |
| EP-0256880-A2 | Alkanoyl esters of heparin of low molecular weight | MIAMI UNIVERSITY (US) | 1988-02-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035997-A1 | KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES | KIT, TEKT1, CUTA | CHRM1 3023/4885CHRM3 2726/4885CHRM2 3420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.