SCHEMBL31676000

SCHEMBL31676000

O=C(O)c1cccc(-c2cnc3cccc(C(=O)Nc4nc5ccccc5s4)c3c2)n1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BCL2L1 Q07817 8/20 0.77
▸ CNR1 P21554 1/20 0.58
▸ ALDH1A1 P00352 3/20 0.54
▸ NPC1 O15118 4/20 0.49
▸ RAB9A P51151 4/20 0.49
▸ SMN1; SMN2 Q16637 3/20 0.49
▸ MEN1 O00255 2/20 0.49
▸ KMT2A Q03164 2/20 0.49
▸ KDM4E B2RXH2 3/20 0.48
▸ LMNA P02545 2/20 0.48
▸ MAPT P10636 2/20 0.48
▸ HPGD P15428 2/20 0.48
▸ ALOX12 P18054 1/20 0.48
▸ DUSP3 P51452 1/20 0.48
▸ PTPN5 P54829 1/20 0.48
▸ PTPN11 Q06124 1/20 0.48
▸ PKM P14618 2/20 0.48
▸ PAX8 Q06710 1/20 0.48
▸ L3MBTL1 Q9Y468 1/20 0.48
▸ HTT P42858 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30885529 0.87 BCL2L1 (1.00) BCL2L1CNR1ALDH1A1NPC1RAB9A
SCHEMBL14808194 0.75 CNR1 (1.00) BCL2L1CNR1ALDH1A1NPC1RAB9A
SCHEMBL2625445 0.72 BCL2L1 (0.60) BCL2L1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL23607124 0.72 CNR1 (0.71) CNR1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL11950436 0.72 MGAM (0.54) BCL2L1CNR1ALDH1A1RAB9AKDM4E
SCHEMBL30037193 0.72 NPC1 (0.70) CNR1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL12768123 0.72 NPC1 (0.70) CNR1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL4916595 0.71 ALDH1A1 (1.00) CNR1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL29074213 0.71 NPC1 (0.62) CNR1NPC1RAB9ASMN1; SMN2MEN1
SCHEMBL30608755 0.71 NPC1 (0.62) CNR1NPC1RAB9ASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263491-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2025-08-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263491-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES EGFR, ERBB2, ERBB3 BCL2L1 31/4885CNR1 2215/4885ALDH1A1 1891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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