SCHEMBL31676894

SCHEMBL31676894

CCc1nc(N)c2[nH]c(OCP(=O)(O)O)nc2n1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FBP1 P09467 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3878333 0.90 FBP1 (0.36) FBP1
SCHEMBL10408921 0.70 ADORA1 (0.46) —
SCHEMBL27405630 0.68 — —
SCHEMBL3417501 0.66 GAA (0.31) —
SCHEMBL4481885 0.65 CCNA2 (0.39) —
SCHEMBL4748203 0.63 HPRT1 (0.36) —
SCHEMBL886934 0.63 PDPK1 (0.40) —
SCHEMBL29708075 0.62 PDPK1 (0.43) —
SCHEMBL3837871 0.62 PDPK1 (0.43) —
SCHEMBL1924592 0.62 PDPK1 (0.59) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12397058-B2 Metabolically stable prodrugs TSRL, INC. (US) 2025-08-26 — — US claimed
US-12397058-B2 Metabolically stable prodrugs TSRL, INC. (US) 2025-08-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12397058-B2 Metabolically stable prodrugs CES1, CES2, CYP2S1 FBP1 218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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