Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 2/20 | 0.41 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30863989 | 0.89 | SOS1 (0.42) | SOS1MLKLCRBNCYP2D6USP2 | |
| SCHEMBL30816879 | 0.86 | SOS1 (0.50) | SOS1MLKLCRBNCYP2D6USP2 | |
| SCHEMBL30267496 | 0.84 | GABRD (0.51) | MLKLCRBNCYP2D6USP2NR3C1 | |
| SCHEMBL21408866 | 0.84 | GABRD (0.51) | MLKLCRBNCYP2D6USP2NR3C1 | |
| SCHEMBL30267244 | 0.84 | SOS1 (0.42) | SOS1MLKLCRBNCYP2D6USP2 | |
| SCHEMBL24735010 | 0.83 | NR3C1 (0.47) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL29841507 | 0.83 | NR3C1 (0.47) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL31447662 | 0.83 | SOS1 (0.44) | SOS1NR3C1PGRSLC6A4KCNH2 | |
| Hydrochloric Acid SCHEMBL29841613 | 0.82 | NR3C1 (0.46) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL31677340 | 0.82 | SOS1 (0.41) | SOS1MLKLCRBNCYP2D6USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4606803-A1 | KRAS G12D DEGRADATION AGENT, AND PREPARATION METHOD AND USE THEREFOR | Leadingtac Pharmaceutical (Shaoxing) Co., Ltd. (CN) | 2025-08-27 | — | — | EP | disclosed |