SCHEMBL31679025

SCHEMBL31679025

CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@@H](CC12CC(C1)C2)C(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(N)=O

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ KLK7 P49862 2/20 0.50
▸ KLK5 Q9Y337 2/20 0.50
▸ PSMB8 P28062 1/20 0.49
▸ PSMB9 P28065 1/20 0.49
▸ PSMB5 P28074 1/20 0.49
▸ CTSL P07711 1/20 0.49
▸ MAPT P10636 1/20 0.46
▸ ITGB3 P05106 1/20 0.46
▸ ITGA2B P08514 1/20 0.46
▸ CCKBR P32239 2/20 0.46
▸ NPY4R P50391 4/20 0.44
▸ HTRA1 Q92743 1/20 0.44
▸ NPY1R P25929 2/20 0.44
▸ NPY2R P49146 2/20 0.44
▸ NPY5R Q15761 2/20 0.44
▸ SIRT2 Q8IXJ6 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30341831 0.97 KLK7 (0.49) KLK7KLK5PSMB8PSMB9PSMB5
SCHEMBL31679039 0.97 KLK7 (0.49) KLK7KLK5PSMB8PSMB9PSMB5
SCHEMBL31679030 0.93 KLK7 (0.49) KLK7KLK5PSMB8PSMB9PSMB5
SCHEMBL22117811 0.92 CTSL (0.51) CTSLNPY4RNPY1RNPY2RNPY5R
SCHEMBL22117557 0.92 CTSL (0.51) CTSLNPY4RNPY1RNPY2RNPY5R
SCHEMBL22117808 0.92 CTSL (0.51) CTSLNPY4RNPY1RNPY2RNPY5R
SCHEMBL22117556 0.92 CTSL (0.51) CTSLNPY4RNPY1RNPY2RNPY5R
SCHEMBL31679023 0.91 CTSL (0.57) KLK7KLK5PSMB8PSMB9PSMB5
SCHEMBL22117451 0.90 PSMB8 (0.46) PSMB8PSMB9PSMB5CCKBRNPY4R
SCHEMBL22117454 0.90 PSMB8 (0.46) PSMB8PSMB9PSMB5CCKBRNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12404300-B2 Mitochondria-targeting peptides STEALTH BIOTHERAPEUTICS INC. (US) 2025-09-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12404300-B2 Mitochondria-targeting peptides SSBP1, HSPE1, IMMT KLK7 4426/4885KLK5 4428/4885PSMB8 2482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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