Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31679843 | 0.89 | POLB (0.55) | MAPTMEN1KMT2APOLBATM | |
| SCHEMBL24875965 | 0.89 | MAPT (0.53) | MAPTMEN1KMT2APOLBATM | |
| SCHEMBL31679873 | 0.89 | MAPT (0.53) | MAPTMEN1KMT2APOLBATM | |
| SCHEMBL31680001 | 0.86 | THRB (0.53) | MAPTMEN1KMT2APOLBATM | |
| SCHEMBL24875967 | 0.86 | THRB (0.53) | MAPTMEN1KMT2APOLBATM | |
| SCHEMBL24875961 | 0.83 | MAPT (0.52) | MAPTMEN1KMT2APOLBATM | |
| SCHEMBL30210960 | 0.83 | MAPT (0.52) | MAPTMEN1KMT2APOLBATM | |
| SCHEMBL31679994 | 0.83 | MAPT (0.47) | MAPTMEN1KMT2APOLBATM | |
| SCHEMBL24876376 | 0.82 | MAPT (0.53) | MAPTMEN1KMT2APOLBATM | |
| SCHEMBL31680017 | 0.82 | MAPT (0.53) | MAPTMEN1KMT2APOLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367103-B1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-09-03 | — | — | EP | disclosed |