Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31679822 | 0.89 | MAPT (0.47) | POLBMEN1KMT2AMAPTATM | |
| SCHEMBL24875965 | 0.89 | MAPT (0.53) | POLBMEN1KMT2ALMNAMAPT | |
| SCHEMBL31679873 | 0.89 | MAPT (0.53) | POLBMEN1KMT2ALMNAMAPT | |
| SCHEMBL31680001 | 0.88 | THRB (0.53) | POLBMEN1KMT2AMAPTATM | |
| SCHEMBL24875967 | 0.88 | THRB (0.53) | POLBMEN1KMT2AMAPTATM | |
| SCHEMBL24876366 | 0.86 | MEN1 (0.58) | POLBMEN1KMT2ALMNAMAPT | |
| SCHEMBL31679893 | 0.86 | MEN1 (0.58) | POLBMEN1KMT2ALMNAMAPT | |
| SCHEMBL31679994 | 0.85 | MAPT (0.47) | POLBMEN1KMT2AMAPTATM | |
| SCHEMBL23493830 | 0.83 | MEN1 (0.67) | POLBMEN1KMT2ALMNAMAPT | |
| SCHEMBL31307838 | 0.83 | MEN1 (0.67) | POLBMEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367103-B1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-09-03 | — | — | EP | disclosed |