Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24875965 | 0.89 | MAPT (0.53) | MAPTATMMEN1KMT2AIDH1 | |
| SCHEMBL31679873 | 0.89 | MAPT (0.53) | MAPTATMMEN1KMT2AIDH1 | |
| SCHEMBL31680001 | 0.86 | THRB (0.53) | MAPTATMMEN1KMT2AIDH1 | |
| SCHEMBL24875967 | 0.86 | THRB (0.53) | MAPTATMMEN1KMT2AIDH1 | |
| SCHEMBL31679843 | 0.85 | POLB (0.55) | MAPTATMMEN1KMT2AIDH1 | |
| SCHEMBL24876322 | 0.85 | MAPT (0.49) | MAPTATMMEN1KMT2AIDH1 | |
| SCHEMBL31679822 | 0.83 | MAPT (0.47) | MAPTATMMEN1KMT2AIDH1 | |
| SCHEMBL24876376 | 0.82 | MAPT (0.53) | MAPTATMMEN1KMT2AIDH1 | |
| SCHEMBL31680017 | 0.82 | MAPT (0.53) | MAPTATMMEN1KMT2AIDH1 | |
| SCHEMBL31679912 | 0.81 | MAPT (0.50) | MAPTATMMEN1KMT2AIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367103-B1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-09-03 | — | — | EP | disclosed |