Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30819798 | 1.00 | CYP1A2 (0.50) | CYP1A2CYP2C19CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL31681025 | 0.83 | CYP1A2 (0.47) | CYP1A2CYP2C19CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL30819807 | 0.83 | CYP1A2 (0.47) | CYP1A2CYP2C19CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL5348242 | 0.79 | CYP1A2 (0.57) | CYP1A2CYP3A4ALDH1A1KDM4EMAPT | |
| SCHEMBL21617914 | 0.78 | LMNA (0.60) | CYP1A2CYP3A4ALDH1A1KDM4EMAPT | |
| SCHEMBL5593842 | 0.78 | CYP1A2 (0.53) | CYP1A2CYP3A4KDM4EMAPTPTPN1 | |
| SCHEMBL18046156 | 0.77 | ALDH1A1 (0.53) | CYP1A2CYP3A4SIRT2ALDH1A1KDM4E | |
| SCHEMBL8610579 | 0.77 | MTNR1A (0.67) | MTNR1A | |
| SCHEMBL1067199 | 0.76 | SIRT2 (0.54) | SIRT2ALDH1A1KDM4ETDP1PTPN1 | |
| SCHEMBL6583329 | 0.76 | F2 (0.46) | CYP1A2CYP2C19CYP2D6CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250276982-A1 | KRAS INHIBITORS | ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) | 2025-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250276982-A1 | KRAS INHIBITORS | KRAS, NRAS, HRAS | CYP1A2 4673/4885CYP2C19 4367/4885CYP2D6 2896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.