Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 2/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 3/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31683110 | 0.89 | HSD17B10 (0.36) | PTGER2LMNAHDAC1HDAC3HDAC2 | |
| SCHEMBL31683224 | 0.87 | HDAC6 (0.36) | PTGER2HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL31683119 | 0.87 | HDAC1 (0.33) | PTGER2HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL31683102 | 0.86 | ALDH1A1 (0.42) | LMNATP53MEN1KMT2AALDH1A1 | |
| SCHEMBL31683129 | 0.83 | GRM2 (0.36) | HDAC1HDAC3HDAC2NCOR2SSTR4 | |
| SCHEMBL31683074 | 0.81 | BACE1 (0.32) | LMNAHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL14185973 | 0.80 | HDAC3 (0.47) | LMNAHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL16794210 | 0.78 | SSTR4 (0.42) | LMNAHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL849068 | 0.78 | SSTR4 (0.41) | HDAC1HDAC3HDAC2NCOR2MEN1 | |
| SCHEMBL31683071 | 0.74 | HDAC1 (0.42) | PTGER2LMNAHDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250282742-A1 | BENZOFURAN DERIVATIVES FOR TARGETING AUTOPHAGY | Automera PTE. LTD (SG) | 2025-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250282742-A1 | BENZOFURAN DERIVATIVES FOR TARGETING AUTOPHAGY | SQSTM1, BECN1, TFEB | PTGER2 4026/4885TBXAS1 922/4885LMNA 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.