SCHEMBL31685198

SCHEMBL31685198

O=C1N=C2C(=NC(=O)N2[C@H]2C[C@H](O)[C@@H](COP(=O)(O)O)O2)C(=O)N1

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TYMS P04818 4/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31685516 0.83 TK1 (0.43) —
SCHEMBL31685171 0.82 TYMS (0.47) TYMS
SCHEMBL31685582 0.82 TYMS (0.46) TYMS
SCHEMBL2991978 0.82 TYMS (0.47) TYMS
SCHEMBL31685178 0.81 UMPS (0.49) —
SCHEMBL31685166 0.80 TYMS (0.45) TYMS
SCHEMBL31685187 0.79 RNASE1 (0.34) TYMS
Tetrabuthylammonium SCHEMBL19462589 0.74 TYMS (0.41) TYMS
SCHEMBL154965 0.74 POLB (0.45) TYMS
SCHEMBL31685165 0.71 ADORA1 (0.39) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 — — US claimed
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 TYMS 3277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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