SCHEMBL31685282

SCHEMBL31685282

CC(=O)Nc1nc2c(ncn2[C@H]2C[C@H](OP(=O)(O)O)[C@@H](CO)O2)c(=O)[nH]1

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.63
▸ TAS1R3 Q7RTX0 1/20 0.61
▸ TAS1R1 Q7RTX1 1/20 0.61
▸ P2RY1 P47900 1/20 0.53
▸ POLA1 P09884 1/20 0.52
▸ POLB P06746 1/20 0.46
▸ MEN1 O00255 1/20 0.44
▸ TSHR P16473 1/20 0.44
▸ KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31685346 0.90 KDM4E (0.59) KDM4ETAS1R3TAS1R1P2RY1POLA1
SCHEMBL29559302 0.86 POLA1 (0.66) KDM4ETAS1R3TAS1R1POLA1
SCHEMBL890293 0.86 POLA1 (0.66) KDM4ETAS1R3TAS1R1POLA1
SCHEMBL31685240 0.86 P2RY1 (0.51) KDM4ETAS1R3TAS1R1P2RY1
SCHEMBL25139386 0.85 KDM4E (0.62) KDM4ETAS1R3TAS1R1P2RY1POLA1
SCHEMBL31685734 0.84 TAS1R3 (0.75) KDM4ETAS1R3TAS1R1P2RY1POLA1
SCHEMBL2985702 0.84 POLB (0.61) KDM4EP2RY1POLB
SCHEMBL31685625 0.83 P2RY1 (0.51) KDM4EP2RY1POLA1POLB
SCHEMBL31685416 0.83 TAS1R3 (0.75) KDM4ETAS1R3TAS1R1
SCHEMBL23225351 0.81 KDM4E (0.77) KDM4ETAS1R3TAS1R1P2RY1POLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 KDM4E 3958/4885TAS1R3 3879/4885TAS1R1 4321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback