SCHEMBL31685308

SCHEMBL31685308

CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)N=C2C(=O)N=C(N)N=C21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.36
▸ ALDH1A1 P00352 2/20 0.36
▸ MTOR P42345 2/20 0.36
▸ TP53 P04637 2/20 0.36
▸ GMNN O75496 1/20 0.36
▸ NFKB1 P19838 1/20 0.36
▸ DNMT1 P26358 1/20 0.36
▸ THPO P40225 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ RAB9A P51151 1/20 0.36
▸ BLM P54132 1/20 0.36
▸ HBB P68871 1/20 0.36
▸ PMP22 Q01453 1/20 0.36
▸ SMN1; SMN2 Q16637 2/20 0.34
▸ THRB P10828 1/20 0.34
▸ MDM2 Q00987 1/20 0.34
▸ NCOA1 Q15788 1/20 0.34
▸ NCOA3 Q9Y6Q9 1/20 0.34
▸ POLB P06746 1/20 0.34
▸ MAPT P10636 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL114650 0.86 LMNA (0.45) LMNAALDH1A1MTORTP53GMNN
SCHEMBL31685759 0.85 LMNA (0.34) LMNAALDH1A1MTORTP53GMNN
SCHEMBL30612476 0.83 EGFR (0.39) LMNAALDH1A1MTORTP53GMNN
Phosphoric Acid SCHEMBL20305093 0.82 LMNA (0.42) LMNAALDH1A1MTORTP53GMNN
Phosphoric Acid SCHEMBL6465085 0.82 LMNA (0.42) LMNAALDH1A1MTORTP53GMNN
SCHEMBL31685351 0.82 MEN1 (0.35) MAPTMEN1KMT2ACDALGALS3
SCHEMBL31685523 0.81 MAPT (0.34) MAPTMEN1KMT2ACDALGALS8
SCHEMBL31685497 0.81 OGA (0.35) MAPTMEN1KMT2ACDALGALS8
SCHEMBL31685168 0.80 ADORA1 (0.42) ADORA1
SCHEMBL9147640 0.76 LMNA (0.44) LMNAALDH1A1MTORTP53GMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 LMNA 240/4885ALDH1A1 1153/4885MTOR 3099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback