SCHEMBL31685352

SCHEMBL31685352

CC(=O)OC[C@H]1O[C@@H](n2cnc3c(=O)ncn(C)c32)[C@H](OC(C)=O)[C@@H]1OC(C)=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.60
▸ LMNA P02545 3/20 0.60
▸ MAPT P10636 3/20 0.60
▸ TP53 P04637 1/20 0.60
▸ TDP1 Q9NUW8 1/20 0.60
▸ SMN1; SMN2 Q16637 2/20 0.53
▸ THRB P10828 1/20 0.53
▸ HIF1A Q16665 1/20 0.53
▸ PRKAB2 O43741 1/20 0.50
▸ PRKAG1 P54619 1/20 0.50
▸ PRKAA2 P54646 1/20 0.50
▸ PRKAA1 Q13131 1/20 0.50
▸ PRKAG3 Q9UGI9 1/20 0.50
▸ PRKAG2 Q9UGJ0 1/20 0.50
▸ PRKAB1 Q9Y478 1/20 0.50
▸ PRKCA P17252 1/20 0.42
▸ AKT1 P31749 1/20 0.42
▸ PTK2 Q05397 1/20 0.42
▸ TSHR P16473 1/20 0.42
▸ KDM4E B2RXH2 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31685829 0.90 ALDH1A1 (0.60) ALDH1A1LMNAMAPTTP53TDP1
SCHEMBL31685402 0.87 ALDH1A1 (0.59) ALDH1A1LMNAMAPTTP53TDP1
SCHEMBL31685577 0.84 ALDH1A1 (0.58) ALDH1A1LMNAMAPTTP53TDP1
SCHEMBL31685309 0.84 LMNA (0.60) ALDH1A1LMNAMAPTTP53TDP1
SCHEMBL31685616 0.84 LMNA (0.65) ALDH1A1LMNAMAPTTP53TDP1
SCHEMBL31685273 0.84 ALDH1A1 (0.58) ALDH1A1LMNAMAPTTP53TDP1
SCHEMBL31685717 0.83 LMNA (0.50) ALDH1A1LMNAMAPTTP53TDP1
SCHEMBL31685499 0.82 LMNA (0.58) ALDH1A1LMNAMAPTTP53TDP1
SCHEMBL31685252 0.81 ALDH1A1 (0.59) ALDH1A1LMNAMAPTTP53TDP1
SCHEMBL31685654 0.81 ALDH1A1 (0.64) ALDH1A1LMNAMAPTTP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 ALDH1A1 1153/4885LMNA 240/4885MAPT 953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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