Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 5/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.60 |
| ▸ | FEN1 | P39748 | 1/20 | 0.60 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22004470 | 1.00 | GSK3B (1.00) | GSK3BPTPN1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL689331 | 0.91 | GSK3B (0.83) | GSK3BPTPN1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL8103554 | 0.86 | GSK3B (0.77) | GSK3BPTPN1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL19331717 | 0.86 | GSK3B (1.00) | GSK3BPTPN1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL7621 | 0.86 | GSK3B (1.00) | GSK3BPTPN1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL18849535 | 0.86 | GSK3B (1.00) | GSK3BPTPN1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL4324217 | 0.85 | GSK3B (0.72) | GSK3BPTPN1SMN1; SMN2MAPTL3MBTL1 | |
| Hydrogen Sulfide SCHEMBL7496567 | 0.84 | GSK3B (0.95) | GSK3BPTPN1SMN1; SMN2MAPTL3MBTL1 | |
| Methane SCHEMBL7161301 | 0.84 | GSK3B (0.95) | GSK3BPTPN1SMN1; SMN2MAPTL3MBTL1 | |
| Bromide SCHEMBL28774450 | 0.84 | GSK3B (0.95) | GSK3BPTPN1SMN1; SMN2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 642 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930622-A | Antitumor matrine hydrazine thiazole derivative and preparation method and application thereof | 南京林业大学 | 2025-05-06 | — | — | CN | claimed |
| CN-115368346-B | 1, 4-benzodioxane-benzimidazole salt compound and synthesis method and application thereof | 曲靖师范学院 | 2024-04-09 | — | — | CN | claimed |
| EP-3958980-B1 | TARGETED NOVEL TRIAZOLOTHIADIAZINE DERIVATIVES FOR THE TREATMENT OF LUNG CANCER | ANADOLU UNIV (TR) | 2023-11-15 | — | — | EP | claimed |
| CN-115368346-A | 1, 4-benzodioxan-benzimidazole salt compound and synthesis method and application thereof | 曲靖师范学院 | 2022-11-22 | — | — | CN | claimed |
| EP-3958980-A1 | TARGETED NOVEL TRIAZOLOTHIADIAZINE DERIVATIVES FOR THE TREATMENT OF LUNG CANCER | Anadolu Universitesi (TR) | 2022-03-02 | — | — | EP | claimed |
| WO-2021257020-A1 | TARGETED NOVEL TRIAZOLOTHIADIAZINE DERIVATIVES FOR THE TREATMENT OF LUNG CANCER | ANADOLU ÜNİVERSİTESİ (TR) | 2021-12-23 | — | — | WO | claimed |
| CN-110305048-A | One kind preparing α-sulfuryl ketone compounds synthetic method by α, α-two bromo ketone one kettle way | 温州大学 | 2019-10-08 | — | — | CN | claimed |
| EP-1140877-A1 | HYPOLIPIDEMIC AND ANTIOXIDANT MORPHOLINE DERIVATIVES | Elpen S.A. . (GR) | 2001-10-10 | — | — | EP | claimed |
| WO-2000042030-A1 | HYPOLIPIDEMIC AND ANTIOXIDANT MORPHOLINE DERIVATIVES | ELPEN S.A. (GR) | 2000-07-20 | — | — | WO | claimed |
| US-12595243-B2 | Modulators of extracellular signal-regulated kinase | GEN1E LIFESCIENCES INC. (US) | 2026-04-07 | — | — | US | disclosed |
| CN-119930622-A | Antitumor matrine hydrazine thiazole derivative and preparation method and application thereof | 南京林业大学 | 2025-05-06 | — | — | CN | disclosed |
| CN-119930535-A | 1,3, 4-Oxadiazole derivative containing biphenyl unit, and preparation method and application thereof | 江苏海洋大学 | 2025-05-06 | — | — | CN | disclosed |
| US-20250136571-A1 | MODULATORS OF EXTRACELLULAR SIGNAL-REGULATED KINASE | GEN1E LIFESCIENCES INC. | 2025-05-01 | — | — | US | disclosed |
| WO-2025085745-A1 | MODULATORS OF EXTRACELLULAR SIGNAL-REGULATED KINASE | GEN1E LIFESCIENCES INC. (US) | 2025-04-24 | — | — | WO | disclosed |
| US-3979440-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1976-09-07 | — | — | US | disclosed |
| US-3962218-A | NOVEL PROSTANOIC ACID DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-06-08 | — | — | US | disclosed |
| US-3955982-A | HYDROCARBONS, HAL | EASTMAN KODAK COMPANY (US) | 1976-05-11 | — | — | US | disclosed |
| US-3936447-A | 7-Acylamino-desacetoxy-cephalosporanic acid esters and their production | BAYER AKTIENGESELLSCHAFT (DT) | 1976-02-03 | — | — | US | disclosed |
| US-3932338-A | POLYOLEFINS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1976-01-13 | — | — | US | disclosed |
| US-3931407-A | ANTIINFLAMMATORY, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250136571-A1 | MODULATORS OF EXTRACELLULAR SIGNAL-REGULATED KINASE | MAP3K20, MAP3K6, CDC42BPG | GSK3B 621/4885PTPN1 1149/4885SMN1; SMN2 4336/4885 |
| US-12595243-B2 | Modulators of extracellular signal-regulated kinase | CDC42BPG, GRK3, ERBB2 | GSK3B 727/4885PTPN1 206/4885SMN1; SMN2 4551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.