Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.71 |
| ▸ | DPP4 | P27487 | 2/20 | 0.63 |
| ▸ | CD38 | P28907 | 2/20 | 0.63 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL316878 | 1.00 | F2 (0.71) | F2DPP4CD38TYRMEN1 | |
| Hydrochloric Acid SCHEMBL3769735 | 1.00 | F2 (0.71) | F2DPP4CD38TYRMEN1 | |
| Hydrochloric Acid SCHEMBL3767542 | 0.99 | F2 (0.70) | F2DPP4CD38TYRMEN1 | |
| SCHEMBL6139298 | 0.99 | F2 (0.72) | F2DPP4CD38TYRMEN1 | |
| SCHEMBL6139200 | 0.99 | F2 (0.72) | F2DPP4CD38TYRMEN1 | |
| SCHEMBL662073 | 0.99 | F2 (0.72) | F2DPP4CD38TYRMEN1 | |
| Hydrochloric Acid SCHEMBL30540085 | 0.97 | F2 (0.73) | F2DPP4CD38TYRMEN1 | |
| SCHEMBL29532883 | 0.96 | F2 (0.75) | F2DPP4CD38TYRMEN1 | |
| Oenin SCHEMBL723403 | 0.93 | CD38 (0.73) | F2DPP4CD38TYRMEN1 | |
| Oenin SCHEMBL1096836 | 0.93 | CD38 (0.73) | F2DPP4CD38TYRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 560 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240010998-A1 | FLAVONE 4'-O-METHYLTRANSFERASE GENE AND USE FOR SAME | SUNTORY HOLDINGS LIMITED (JP) | 2024-01-11 | — | — | US | claimed |
| WO-2023219526-A1 | MULTITARGET ANTIVIRAL DIETARY SUPPLEMENT | PROKIN MILAN (RS) | 2023-11-16 | — | — | WO | claimed |
| US-20230355769-A1 | COMPOSITIONS, CONTAINERS, AND METHODS RELATED TO FLAVYLIUM EXCIPIENTS | Natural Extraction Systems, LLC (US) | 2023-11-09 | — | — | US | claimed |
| US-20230338331-A1 | COMPOSITIONS, CONTAINERS, AND METHODS RELATED TO FLAVYLIUM EXCIPIENTS | Natural Extraction Systems, LLC (US) | 2023-10-26 | — | — | US | claimed |
| EP-4249597-A1 | FLAVONE 4'-O-METHYLTRANSFERASE GENE AND USE FOR SAME | Suntory Holdings Limited (JP) | 2023-09-27 | — | — | EP | claimed |
| WO-2023128999-A1 | NATURAL COMPOUNDS WITH ANTI-INFLAMMATORY EFFECT | ISTANBUL MEDIPOL UNIVERSITESI TEKNOLOJI TRANSFER OFISI ANONIM SIRKETI (TR) | 2023-07-06 | — | — | WO | claimed |
| WO-2023128988-A1 | INHIBITORY EFFECTS OF STANDARDIZED EXTRACTS OF MALVA SYLVESTRIS FLOWERS ON COX-1, COX-2 AND LOX ENZYMES | ISTANBUL MEDIPOL UNIVERSITESI TEKNOLOJI TRANSFER OFISI ANONIM SIRKETI (TR) | 2023-07-06 | — | — | WO | claimed |
| US-11033597-B2 | Dermatological kit comprising compositions based on hibiscus flower and buriti oil | MEDICAL BRANDS RESEARCH B.V. (NL) | 2021-06-15 | — | — | US | claimed |
| US-20200405797-A1 | TRANSMUCOSAL DELIVERY DEVICE AND METHOD OF MANUFACTURING SAME | NANOSTRIPS, INC. (US) | 2020-12-31 | — | — | US | claimed |
| US-10640176-B1 | Observation system and method for re-suspension quantity of submarine sediments by deep-sea internal waves | OCEAN UNIVERSITY OF CHINA (CN) | 2020-05-05 | — | — | US | claimed |
| WO-2005099721-A2 | COMPOSITIONS COMPRISING PLANT-DERIVED POLYPHENOLIC COMPOUNDS AND INHIBITORS OF REACTIVE OXYGEN SPECIES AND METHODS OF USING THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-10-27 | — | — | WO | claimed |
| EP-1507461-A1 | DIETARY SUPPLEMENTS FROM WINE VINASSES AND RELEVANT PRODUCTION PROCESS | Advance Holdings Limited (ML) | 2005-02-23 | — | — | EP | claimed |
| US-20040259816-A1 | Compositions comprising plant-derived polyphenolic compounds and inhibitors of reactive oxygen species and methods of using thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-12-23 | — | — | US | claimed |
| US-20040166179-A1 | Dietary supplements from wine vinasses and relevant production process | ADVANCE HOLDINGS LIMITED (MT) | 2004-08-26 | — | — | US | claimed |
| US-20040063648-A1 | Compositions comprising plant-derived polyphenolic compounds and inhibitors of reactive oxygen species and methods of using thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-04-01 | — | — | US | claimed |
| WO-2003099040-A1 | DIETARY SUPPLEMENTS FROM WINE VINASSES AND RELEVANT PRODUCTION PROCESS | ADVANCE HOLDINGS LIMITED (MT) | 2003-12-04 | — | — | WO | claimed |
| EP-0496349-B1 | Coating solution for preventing adhesion of polymer scale and method for its use | SHINETSU CHEMICAL CO (JP) | 1996-04-10 | — | — | EP | claimed |
| EP-0496349-A1 | Coating solution for preventing adhesion of polymer scale and method for its use | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1992-07-29 | — | — | EP | claimed |
| EP-0242892-B1 | PROCESS FOR ACTIVATING RHIZOBIUM NODULATION PROMOTERS | Rijksuniversiteit Leiden (NL) | 1991-11-21 | — | — | EP | claimed |
| EP-0242892-A1 | Process for activating rhizobium nodulation promoters | Rijksuniversiteit Leiden (NL) | 1987-10-28 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230355769-A1 | COMPOSITIONS, CONTAINERS, AND METHODS RELATED TO FLAVYLIUM EXCIPIENTS | CNR2, CNR1, UGT8 | ACHE 3117/4885F2 50/4885DPP4 4789/4885 |
| US-20230338331-A1 | COMPOSITIONS, CONTAINERS, AND METHODS RELATED TO FLAVYLIUM EXCIPIENTS | CNR2, CNR1, UGT8 | ACHE 3117/4885F2 50/4885DPP4 4789/4885 |
| US-20040259816-A1 | Compositions comprising plant-derived polyphenolic compounds and inhibitors of reactive oxygen species and methods of using thereof | NFKBIA, NFRKB, NFKB2 | ACHE 460/4885F2 657/4885DPP4 1722/4885 |
| US-20040063648-A1 | Compositions comprising plant-derived polyphenolic compounds and inhibitors of reactive oxygen species and methods of using thereof | NQO1, COMT, LPO | ACHE 75/4885F2 790/4885DPP4 1590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.