Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.71 |
| ▸ | DPP4 | P27487 | 2/20 | 0.63 |
| ▸ | CD38 | P28907 | 2/20 | 0.63 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL316878 | 1.00 | F2 (0.71) | F2DPP4CD38TYRMEN1 | |
| Hydrochloric Acid SCHEMBL316879 | 1.00 | F2 (0.71) | F2DPP4CD38TYRMEN1 | |
| Hydrochloric Acid SCHEMBL3767542 | 0.99 | F2 (0.70) | F2DPP4CD38TYRMEN1 | |
| SCHEMBL6139298 | 0.99 | F2 (0.72) | F2DPP4CD38TYRMEN1 | |
| SCHEMBL6139200 | 0.99 | F2 (0.72) | F2DPP4CD38TYRMEN1 | |
| SCHEMBL662073 | 0.99 | F2 (0.72) | F2DPP4CD38TYRMEN1 | |
| Hydrochloric Acid SCHEMBL30540085 | 0.97 | F2 (0.73) | F2DPP4CD38TYRMEN1 | |
| SCHEMBL29532883 | 0.96 | F2 (0.75) | F2DPP4CD38TYRMEN1 | |
| Oenin SCHEMBL723403 | 0.93 | CD38 (0.73) | F2DPP4CD38TYRMEN1 | |
| Oenin SCHEMBL1096836 | 0.93 | CD38 (0.73) | F2DPP4CD38TYRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130078202-A1 | INHIBITION OF THE FORMATION OF AGEs | BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) | 2013-03-28 | — | — | US | disclosed |
| US-20100316743-A1 | INHIBITION OF THE FORMATION OF AGEs | BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) | 2010-12-16 | — | — | US | disclosed |
| CN-101686954-A | The inhibition that AGE forms | BASF BEAUTY CARE SOLUTIONS F | 2010-03-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100316743-A1 | INHIBITION OF THE FORMATION OF AGEs | AGER, GLA, S100A6 | ACHE 424/4885F2 941/4885DPP4 192/4885 |
| US-20130078202-A1 | INHIBITION OF THE FORMATION OF AGEs | AGER, GLA, S100A6 | ACHE 424/4885F2 941/4885DPP4 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.