Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31688011 | 0.88 | HSD17B10 (0.38) | BRD4BRD2BRD3HAVCR2ALDH1A1 | |
| SCHEMBL27192437 | 0.83 | EGLN3 (0.34) | BRD4BRD2BRD3JAK2JAK1 | |
| SCHEMBL31688018 | 0.79 | SCN9A (0.32) | JAK2JAK1TYK2JAK3GRM4 | |
| SCHEMBL27192094 | 0.73 | ALDH1A1 (0.47) | BRD4BRD2BRD3GRM4ALDH1A1 | |
| SCHEMBL27192415 | 0.73 | ALDH1A1 (0.43) | BRD4BRD2BRD3HAVCR2ALDH1A1 | |
| SCHEMBL27192383 | 0.73 | ALDH1A1 (0.41) | BRD4BRD2BRD3HAVCR2ALDH1A1 | |
| SCHEMBL27380409 | 0.72 | HSD17B10 (0.42) | BRD4BRD2BRD3HAVCR2ALDH1A1 | |
| SCHEMBL31688009 | 0.72 | NPBWR1 (0.36) | GRM4ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL27191940 | 0.71 | HAVCR2 (0.34) | BRD4BRD2BRD3HAVCR2ALDH1A1 | |
| SCHEMBL31687997 | 0.71 | CYP1A1 (0.44) | ALDH1A1KDM4EHPGDSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250296936-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2025-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250296936-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | ACE2, TMPRSS2, ACE | BRD4 1703/4885BRD2 1344/4885BRD3 2788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.