Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.30 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31688006 | 0.90 | NPBWR1 (0.36) | GRM4P2RX3CYP3A4NPBWR1CYP2C9 | |
| SCHEMBL31687992 | 0.86 | PRKDC (0.30) | P2RX3PRKDC | |
| SCHEMBL27192044 | 0.85 | CYP3A4 (0.32) | SCN9AJAK2JAK1TYK2JAK3 | |
| SCHEMBL31688010 | 0.83 | NPBWR1 (0.36) | GRM4P2RX3NPBWR1CYP1A2ALDH1A1 | |
| SCHEMBL31688002 | 0.79 | BRD4 (0.34) | SCN9AJAK2JAK1TYK2JAK3 | |
| SCHEMBL31688019 | 0.78 | NPBWR1 (0.34) | NPBWR1 | |
| SCHEMBL31688009 | 0.77 | NPBWR1 (0.36) | GRM4NPBWR1CYP1A2ALDH1A1HPGD | |
| SCHEMBL27192020 | 0.75 | P2RX7 (0.34) | GRM4P2RX3CYP3A4NPBWR1CYP2C9 | |
| SCHEMBL27192025 | 0.75 | CYP1A2 (0.32) | P2RX3CYP3A4CYP2C9CYP1A2ALDH1A1 | |
| SCHEMBL30702030 | 0.74 | P2RX3 (0.31) | SCN9AGRM4P2RX3CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250296936-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2025-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250296936-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | ACE2, TMPRSS2, ACE | SCN9A 2499/4885JAK2 1994/4885JAK1 1583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.