SCHEMBL31689803

CC[C@H](C)[C@H](NC(=O)[C@H](COC(C)(C)C)NC(=O)[C@H](Cc1ccc(OC(C)(C)C)cc1)NC(=O)[C@H](CC(=O)OC(C)(C)C)NC(=O)[C@H](COC(C)(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)C(C)(C)NC(=O)[C@H](Cc1ccc(OC(C)(C)C)cc1)NC(=O)OC(C)(C)C)[C@@H](C)OC(C)(C)C)[C@@H](C)OC(C)(C)C)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	PSEN1	P49768	15/20	0.42

▸	PSEN2	P49810	15/20	0.42

▸	APH1B	Q8WW43	15/20	0.42

▸	NCSTN	Q92542	15/20	0.42

▸	APH1A	Q96BI3	15/20	0.42

▸	PSENEN	Q9NZ42	15/20	0.42

▸	CTSD	P07339	2/20	0.38

▸	REN	P00797	2/20	0.37

▸	OPRM1	P35372	2/20	0.37

▸	OPRD1	P41143	2/20	0.37

▸	OPRK1	P41145	2/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31456933	0.95	OPRM1 (0.39)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL38652065	0.95	PSEN1 (0.43)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL31689802	0.94	OPRD1 (0.40)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL31536385	0.94	OPRM1 (0.39)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30887319	0.94	PSEN1 (0.43)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL31247960	0.90	OPRD1 (0.40)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL31247966	0.90	OPRM1 (0.40)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL31518747	0.90	PSEN1 (0.47)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL31518743	0.90	PSEN1 (0.47)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL31247969	0.89	ABCB1 (0.40)	PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4624486-A1	POLYPEPTIDE HAVING MODIFIED STRUCTURE AND USE THEREOF	Guangdong Raynovent Biotech Co., Ltd. (CN)	2025-10-01	—	—	EP	disclosed