SCHEMBL31456933

C[C@@H](OC(C)(C)C)[C@H](NC(=O)CNC(=O)[C@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)C(C)(C)NC(=O)[C@H](Cc1ccc(OC(C)(C)C)cc1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](COC(C)(C)C)C(=O)N[C@@H](CC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1ccc(OC(C)(C)C)cc1)C(=O)N[C@@H](COC(C)(C)C)C(=O)O)[C@@H](C)OC(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 19)

	gene	UniProt	supporting neighbours	confidence
▸	OPRM1	P35372	5/20	0.39

▸	OPRD1	P41143	5/20	0.39

▸	OPRK1	P41145	5/20	0.39

▸	PSEN1	P49768	9/20	0.38

▸	PSEN2	P49810	9/20	0.38

▸	APH1B	Q8WW43	9/20	0.38

▸	NCSTN	Q92542	9/20	0.38

▸	APH1A	Q96BI3	9/20	0.38

▸	PSENEN	Q9NZ42	9/20	0.38

▸	ABCB1	P08183	1/20	0.37

▸	CCKAR	P32238	3/20	0.36

▸	CCKBR	P32239	3/20	0.36

▸	REN	P00797	1/20	0.36

▸	PSMB1	P20618	1/20	0.35

▸	PSMB8	P28062	1/20	0.35

▸	PSMB9	P28065	1/20	0.35

▸	PSMB5	P28074	1/20	0.35

▸	PSMB10	P40306	1/20	0.35

▸	PSMB2	P49721	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31536385	0.97	OPRM1 (0.39)	OPRM1OPRD1OPRK1PSEN1PSEN2
SCHEMBL31689803	0.95	PSEN1 (0.42)	OPRM1OPRD1OPRK1PSEN1PSEN2
SCHEMBL31247960	0.95	OPRD1 (0.40)	OPRM1OPRD1OPRK1PSEN1PSEN2
SCHEMBL31247966	0.94	OPRM1 (0.40)	OPRM1OPRD1OPRK1PSEN1PSEN2
SCHEMBL31247969	0.93	ABCB1 (0.40)	OPRM1OPRD1OPRK1PSEN1PSEN2
SCHEMBL31247896	0.92	PSEN1 (0.40)	OPRM1OPRD1OPRK1PSEN1PSEN2
SCHEMBL30887319	0.91	PSEN1 (0.43)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL31296842	0.90	CCKBR (0.41)	OPRM1OPRD1OPRK1PSEN1PSEN2
SCHEMBL38652065	0.90	PSEN1 (0.43)	OPRM1OPRD1OPRK1PSEN1PSEN2
SCHEMBL31689802	0.90	OPRD1 (0.40)	OPRM1OPRD1OPRK1PSEN1PSEN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-119656289-A	Polypeptide with modified structure and application thereof	广东众生睿创生物科技有限公司	2025-03-21	—	—	CN	disclosed