Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27757079 | 0.83 | HSD11B1 (0.40) | PHGDHTRPA1MALT1TRPV1HSD11B1 | |
| SCHEMBL13356063 | 0.82 | HSD11B1 (0.39) | PHGDHTRPA1MALT1TRPV1HSD11B1 | |
| SCHEMBL28760954 | 0.73 | TRPA1 (0.50) | TRPA1MALT1TRPV1HSD11B1KCNH2 | |
| SCHEMBL28203428 | 0.68 | HSD11B1 (0.54) | TRPA1MALT1TRPV1HSD11B1 | |
| SCHEMBL31348096 | 0.68 | HSD11B1 (0.54) | TRPA1MALT1TRPV1HSD11B1 | |
| SCHEMBL13484031 | 0.68 | HSD11B1 (0.40) | PHGDHTRPA1MALT1TRPV1HSD11B1 | |
| SCHEMBL30980825 | 0.67 | CYP1A2 (0.56) | TRPA1MALT1TRPV1HSD11B1 | |
| SCHEMBL8299219 | 0.67 | LMNA (0.59) | TRPA1MALT1TRPV1HSD11B1LMNA | |
| SCHEMBL3559872 | 0.66 | HSD11B1 (0.51) | TRPA1MALT1TRPV1HSD11B1KCNH2 | |
| SCHEMBL30417104 | 0.66 | HSD11B1 (0.48) | TRPA1MALT1TRPV1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4017847-B1 | PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID DERIVATIVES OF 3-BROMO-4,5-DIHYDRO-1H-PYRAZOLES | FMC CORP (US) | 2025-10-01 | — | — | EP | claimed |