Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | MAX | P61244 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27037558 | 0.91 | POLB (0.48) | DGAT1MEN1MAPTKMT2ACYP19A1 | |
| SCHEMBL25238314 | 0.89 | CYP19A1 (0.44) | DGAT1MEN1MAPTKMT2ACYP19A1 | |
| SCHEMBL30566075 | 0.89 | CYP19A1 (0.44) | DGAT1MEN1MAPTKMT2ACYP19A1 | |
| SCHEMBL17474563 | 0.82 | DGAT1 (0.54) | DGAT1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL18582781 | 0.82 | HTR6 (0.48) | MEN1MAPTKMT2ACYP19A1POLB | |
| SCHEMBL23794225 | 0.82 | DGAT1 (0.50) | DGAT1MEN1MAPTKMT2ACYP19A1 | |
| SCHEMBL31748489 | 0.80 | DGAT1 (0.52) | DGAT1MAPTTDP1L3MBTL1LPL | |
| SCHEMBL3033971 | 0.80 | ALDH1A1 (0.45) | MAPTTDP1L3MBTL1LPLLIPG | |
| SCHEMBL182480 | 0.79 | DGAT1 (0.51) | DGAT1KMT2AHTR1AADRA1DADRA1A | |
| SCHEMBL15884409 | 0.79 | EGFR (0.52) | DGAT1MEN1KMT2ACTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304549-A1 | HYDROXYAMIDE DERIVATIVE AND USE THEREOF | SICHUAN HUIYU PHARMACEUTICAL CO., LTD. (CN) | 2025-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304549-A1 | HYDROXYAMIDE DERIVATIVE AND USE THEREOF | HDAC1, HDAC11, HDAC5 | DGAT1 2063/4885MEN1 3640/4885MAPT 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.