Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3178719 | 1.00 | CYP2C19 (0.43) | CYP2C19CXCR3KCNH2JAK3FLT3 | |
| SCHEMBL3184309 | 0.86 | CYP2C19 (0.52) | CYP2C19CXCR3LIMK2CYP3A4CYP2D6 | |
| SCHEMBL3176149 | 0.86 | CYP2C19 (0.52) | CYP2C19CXCR3LIMK2CYP3A4CYP2D6 | |
| SCHEMBL10849119 | 0.76 | GRM1 (0.47) | CYP2C19ALDH1A1KDM4EHSD17B10GRM1 | |
| SCHEMBL7980393 | 0.74 | MAP4K4 (0.48) | CYP2C19CXCR3KDM4ECYP3A4CYP2D6 | |
| SCHEMBL3227404 | 0.73 | ROCK1 (0.43) | CYP2C19KCNMA1MEN1KMT2ACYP3A4 | |
| SCHEMBL10371961 | 0.73 | MAPT (0.41) | ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL3222860 | 0.72 | KCNMA1 (0.41) | CYP2C19KCNMA1MEN1KMT2AIRAK4 | |
| SCHEMBL3628431 | 0.71 | FLT3 (0.47) | FLT3KDM4EMEN1LMNAKMT2A | |
| SCHEMBL3185289 | 0.71 | PRKCQ (0.42) | CYP2C19ALDH1A1KCNMA1LMNARPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016297-A1 | ALKYL-SUBSTITUTED 3' COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016297-A1 | ALKYL-SUBSTITUTED 3' COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | HTR6, HTR3B, HTR3A | CYP2C19 319/4885CXCR3 907/4885KCNH2 1058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.