Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 4/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.33 |
| ▸ | MTOR | P42345 | 4/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | WNT1 | P04628 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26685697 | 0.90 | MAPK1 (0.37) | MAPK1TYRO3PIK3CAMTORDGAT2 | |
| SCHEMBL30632637 | 0.90 | MAPK1 (0.37) | MAPK1TYRO3PIK3CAMTORDGAT2 | |
| SCHEMBL26685819 | 0.89 | MAPK1 (0.37) | MAPK1TYRO3PIK3CAMTORDGAT2 | |
| SCHEMBL31543335 | 0.89 | MAPK1 (0.37) | MAPK1TYRO3PIK3CAMTORDGAT2 | |
| SCHEMBL30632721 | 0.89 | MAPK1 (0.37) | MAPK1TYRO3PIK3CAMTORDGAT2 | |
| SCHEMBL26685795 | 0.83 | ALDH1A1 (0.34) | TYRO3RXRARXRBRXRGCYP4F2 | |
| SCHEMBL30632664 | 0.83 | ALDH1A1 (0.34) | TYRO3RXRARXRBRXRGCYP4F2 | |
| SCHEMBL26685658 | 0.80 | CYP4F2 (0.33) | DGAT2RXRARXRBRXRGCYP4F2 | |
| SCHEMBL31543464 | 0.79 | RXRA (0.35) | RXRARXRBRXRGCYP4F2CYP4A11 | |
| SCHEMBL30632780 | 0.79 | OPRK1 (0.39) | MAPK1TYRO3PIK3CAMTORDGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304577-A1 | TYK2 INHIBITORS | BIOGEN MA INC. | 2025-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304577-A1 | TYK2 INHIBITORS | TYK2, JAK2, JAK1 | MAPK1 228/4885TYRO3 11/4885PIK3CA 607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.