Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | YAP1 | P46937 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | NAE1 | Q13564 | 1/20 | 0.40 |
| ▸ | UBA3 | Q8TBC4 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7623319 | 0.91 | KDM1A (0.44) | MCHR2IDO1YAP1NAE1UBA3 | |
| SCHEMBL8314335 | 0.91 | KDM1A (0.44) | MCHR2IDO1YAP1NAE1UBA3 | |
| SCHEMBL12084830 | 0.81 | KDM1A (0.46) | MCHR2IDO1LMNANAE1UBA3 | |
| SCHEMBL31693987 | 0.81 | MCHR2 (0.35) | P2RX7MCHR2TP53IDO1LMNA | |
| SCHEMBL31694103 | 0.80 | MCHR2 (0.34) | MCHR2RORC | |
| SCHEMBL14272800 | 0.80 | MC4R (0.60) | MC4R | |
| SCHEMBL14300913 | 0.80 | MC4R (0.60) | MC4R | |
| SCHEMBL31693849 | 0.77 | HSD11B1 (0.49) | GPR119CNR1CNR2 | |
| SCHEMBL31693853 | 0.77 | HSD11B1 (0.49) | GPR119CNR1CNR2 | |
| SCHEMBL9994136 | 0.76 | NAMPT (0.48) | P2RX7GPR119TACR1YAP1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025201477-A1 | SPIROCYCLIC GSDME INHIBITORS | PYROTECH (BEIJING) BIOTECHNOLOGY CO.,LTD. (CN) | 2025-10-02 | — | — | WO | disclosed |