Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31693869 | 0.83 | HSD11B1 (0.34) | RORC | |
| SCHEMBL31693987 | 0.83 | MCHR2 (0.35) | MCHR2RORCCASP1SIGMAR1TMEM97 | |
| SCHEMBL31694051 | 0.83 | KDM1A (0.35) | RORC | |
| SCHEMBL31694021 | 0.81 | HRH3 (0.31) | — | |
| SCHEMBL31693878 | 0.80 | P2RX7 (0.44) | MCHR2RORC | |
| SCHEMBL31694185 | 0.79 | MCHR2 (0.30) | MCHR2 | |
| SCHEMBL31693927 | 0.75 | HTR7 (0.36) | — | |
| SCHEMBL31694054 | 0.73 | HSD11B1 (0.35) | RORCSIGMAR1TMEM97DRD2 | |
| SCHEMBL7623319 | 0.72 | KDM1A (0.44) | MCHR2 | |
| SCHEMBL8314335 | 0.72 | KDM1A (0.44) | MCHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025201477-A1 | SPIROCYCLIC GSDME INHIBITORS | PYROTECH (BEIJING) BIOTECHNOLOGY CO.,LTD. (CN) | 2025-10-02 | — | — | WO | disclosed |