Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16798560 | 0.90 | CNR2 (0.38) | PPARDPPARAPPARG | |
| SCHEMBL16798425 | 0.89 | LDHA (0.48) | PPARDPPARAPPARG | |
| SCHEMBL16798256 | 0.86 | PPARA (0.39) | PPARDPPARAPPARGMMEACE | |
| SCHEMBL31694102 | 0.84 | MAOA (0.36) | RIPK1MAOAMAOBMMEACE | |
| SCHEMBL16798242 | 0.83 | KMT2A (0.44) | PPARAPPARGMME | |
| SCHEMBL16798290 | 0.81 | CTSL (0.42) | RIPK1PPARAPPARG | |
| SCHEMBL4698511 | 0.81 | CYP1A2 (0.54) | MMECPA1 | |
| SCHEMBL16798289 | 0.78 | PPARA (0.47) | PPARAPPARG | |
| SCHEMBL21797574 | 0.77 | CYP1A2 (0.49) | MMECPA1 | |
| SCHEMBL31021791 | 0.77 | PPARA (0.40) | PPARDPPARAPPARGPTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025201477-A1 | SPIROCYCLIC GSDME INHIBITORS | PYROTECH (BEIJING) BIOTECHNOLOGY CO.,LTD. (CN) | 2025-10-02 | — | — | WO | disclosed |