Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 15/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27361103 | 1.00 | MRGPRX4 (0.53) | MRGPRX4MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL31695373 | 0.89 | ALOX5AP (0.43) | MRGPRX4MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL27361439 | 0.89 | ALOX5AP (0.43) | MRGPRX4MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL27361097 | 0.86 | MRGPRX4 (0.54) | MRGPRX4RAB9ASMN1; SMN2TP53PKM | |
| SCHEMBL27363026 | 0.85 | MRGPRX4 (0.60) | MRGPRX4RAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL27363115 | 0.84 | MRGPRX4 (0.65) | MRGPRX4 | |
| SCHEMBL31695369 | 0.78 | PTPN7 (0.54) | MRGPRX4MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL27361265 | 0.78 | PTPN7 (0.54) | MRGPRX4MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL27361424 | 0.76 | MAPT (0.42) | MRGPRX4MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL16829529 | 0.75 | MAPT (0.61) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250313532-A1 | ALDH2 INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE | 2025-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250313532-A1 | ALDH2 INHIBITORS AND METHODS OF USE THEREOF | ADH1A, ALDH1A1, ADH1C | MRGPRX4 4547/4885MEN1 4378/4885KMT2A 2253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.