SCHEMBL3169986

SCHEMBL3169986

COc1sc(-c2ccccc2)cc1C1=C(F)C(F)(F)C(F)(F)C1(F)F

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
HPGD P15428 2/20 0.36
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 1/20 0.36
TSHR P16473 1/20 0.36
PTP4A3 O75365 2/20 0.33
MAPT P10636 4/20 0.32
GAA P10253 2/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
PTP4A2 Q12974 1/20 0.32
PTP4A1 Q93096 1/20 0.32
HSD17B1 P14061 2/20 0.31
KDM4E B2RXH2 3/20 0.31
PLAU P00749 1/20 0.31
C1S P09871 1/20 0.31
PLCG2 P16885 1/20 0.31
POLB P06746 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1041118 0.92 ALDH1A1 (0.37) ALDH1A1HPGDRAB9ASMN1; SMN2NPC1
SCHEMBL3361316 0.86 PLA2G10 (0.36) ALDH1A1HPGDRAB9ASMN1; SMN2NPC1
SCHEMBL3166027 0.84 ALDH1A1 (0.32) ALDH1A1HPGDRAB9ASMN1; SMN2NPC1
SCHEMBL3008443 0.82 PLA2G10 (0.38) ALDH1A1HPGDRAB9ASMN1; SMN2NPC1
SCHEMBL14838322 0.81 HSD17B1 (0.43) PTP4A3MAPTPTP4A2PTP4A1HSD17B1
SCHEMBL10101123 0.80 APP (0.45) ALDH1A1HPGDRAB9ASMN1; SMN2NPC1
SCHEMBL23158843 0.79 PTP4A3 (0.33) ALDH1A1HPGDRAB9ASMN1; SMN2NPC1
SCHEMBL3965411 0.77 ALDH1A1 (0.36) ALDH1A1HPGDRAB9ASMN1; SMN2NPC1
SCHEMBL13715047 0.77 HSD17B1 (0.35) ALDH1A1HPGDRAB9ASMN1; SMN2NPC1
SCHEMBL9034121 0.75 APP (0.41) ALDH1A1HPGDRAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7645558-B2 Inkless reimageable printing paper and method XEROX CORPORATION (US) 2010-01-12 US disclosed
US-7645558-B2 Inkless reimageable printing paper and method XEROX CORPORATION (US) 2010-01-12 US disclosed
US-7645558-B2 Inkless reimageable printing paper and method XEROX CORPORATION (US) 2010-01-12 US disclosed
US-20080311494-A1 INKLESS REIMAGEABLE PRINTING PAPER AND METHOD XEROX CORPORATION (US) 2008-12-18 US disclosed
US-20080311494-A1 INKLESS REIMAGEABLE PRINTING PAPER AND METHOD XEROX CORPORATION (US) 2008-12-18 US disclosed
US-20080311494-A1 INKLESS REIMAGEABLE PRINTING PAPER AND METHOD XEROX CORPORATION (US) 2008-12-18 US disclosed
EP-2003497-A1 Inkless reimageable printing paper and method Xerox Corporation (US) 2008-12-17 EP disclosed
CN-1231758-C Method for manipulating microcarriers for identification purposes TEBOTEC N V (BE) 2005-12-14 CN disclosed
CN-1481505-A Method and device for manipulation of microcarriers for identification purpose ̩ 2004-03-10 CN disclosed