Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.41 |
| ▸ | IKBKB | O14920 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2990966 | 0.92 | APP (0.45) | APPIKBKBNPC1RAB9AALDH1A1 | |
| SCHEMBL20089651 | 0.88 | APP (0.41) | APPIKBKBNPC1RAB9AALDH1A1 | |
| SCHEMBL15926425 | 0.86 | APP (0.40) | APPIKBKBNPC1RAB9AALDH1A1 | |
| SCHEMBL9033357 | 0.85 | GCGR (0.39) | APPNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL3008443 | 0.84 | PLA2G10 (0.38) | NPC1RAB9AALDH1A1HPGDMAPT | |
| SCHEMBL13163334 | 0.83 | APP (0.43) | APPIKBKBNPC1RAB9AALDH1A1 | |
| SCHEMBL13164320 | 0.82 | BACE1 (0.44) | APPIKBKBNPC1RAB9AALDH1A1 | |
| SCHEMBL9113239 | 0.82 | CDC7 (0.39) | — | |
| SCHEMBL3858306 | 0.81 | APP (0.35) | APPIKBKBNPC1RAB9AALDH1A1 | |
| SCHEMBL14833740 | 0.79 | THRB (0.35) | APPMAPTSMN1; SMN2ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104292234-B | Asymmetric perfluorocyclopentene photochromic fluorescent probe compound containing benzimidazole group as well as preparation method and application of asymmetric perfluorocyclopentene photochromic fluorescent probe compound | 江西科技师范大学 | 2017-03-22 | — | — | CN | disclosed |
| EP-0717740-A1 | PHOTOCHROMIC COMPOUNDS, METHODS AND INTERMEDIATES FOR PRODUCING THEM AND THEIR USE | Ciba SC Holding AG (CH) | 1996-06-26 | — | — | EP | disclosed |
| WO-1995007275-A1 | PHOTOCHROMIC COMPOUNDS, METHODS AND INTERMEDIATES FOR PRODUCING THEM AND THEIR USE | CIBA-GEIGY AG (CH) | 1995-03-16 | — | — | WO | disclosed |