Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.61 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78614 | 0.80 | SELL (0.52) | ERN1KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL3424158 | 0.78 | ERN1 (0.54) | ERN1DGAT1KDM4EMAPTALDH1A1 | |
| SCHEMBL30211643 | 0.78 | ERN1 (0.54) | ERN1DGAT1KDM4EMAPTALDH1A1 | |
| SCHEMBL14690903 | 0.77 | ERN1 (0.38) | ERN1KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL12767106 | 0.76 | ERN1 (1.00) | ERN1DGAT1KDM4EMAPTALDH1A1 | |
| SCHEMBL7950797 | 0.74 | AKR1B1 (0.43) | ERN1DGAT1KDM4EMAPTALDH1A1 | |
| SCHEMBL10964657 | 0.74 | ERN1 (0.43) | ERN1DGAT1KDM4EMAPTALDH1A1 | |
| SCHEMBL1996333 | 0.74 | ERN1 (0.52) | ERN1DGAT1KDM4EMAPTALDH1A1 | |
| SCHEMBL31700607 | 0.74 | ERN1 (0.52) | ERN1DGAT1KDM4EMAPTALDH1A1 | |
| SCHEMBL8769707 | 0.74 | ERN1 (0.43) | ERN1DGAT1KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250319056-A1 | METHODS FOR TREATING CANCER | UNIV INDIANA TRUSTEES (US) | 2025-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250319056-A1 | METHODS FOR TREATING CANCER | HSP90AB1, HSP90B1, HSP90AB2P | ERN1 2613/4885DGAT1 2057/4885KDM4E 3488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.