Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 5/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10964657 | 0.87 | ERN1 (0.43) | AKR1B1ERN1KDM4EMAPTMEN1 | |
| SCHEMBL605556 | 0.80 | AKR1C3 (0.57) | AKR1B1KDM4ECA1CA2CA4 | |
| SCHEMBL30555489 | 0.80 | AKR1C3 (0.57) | AKR1B1KDM4ECA1CA2CA4 | |
| SCHEMBL16644420 | 0.76 | DGAT1 (0.46) | ERN1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL7526167 | 0.74 | DGAT1 (0.38) | ERN1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL31700545 | 0.74 | ERN1 (0.61) | ERN1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL895511 | 0.74 | AKR1C4 (0.67) | ERN1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL19423432 | 0.74 | HSD17B10 (0.47) | ERN1KDM4EMAPTMEN1KMT2A | |
| Brosotamide SCHEMBL2734625 | 0.71 | KDM4E (0.51) | ERN1KDM4EMAPTMEN1KMT2A | |
| Brosotamide SCHEMBL11765006 | 0.69 | KDM4E (0.50) | ERN1KDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001079349-A1 | UREA MOULDING COMPOUNDS WITH ANTISEPTIC ACTIVITY | PERSTORP CHEMITEC S.P.A. (IT) | 2001-10-25 | — | — | WO | claimed |
| CN-1612723-A | Topical compositions comprising enzyme stabilized by inhibitor | PROCTER & GAMBLE (US) | 2005-05-04 | — | — | CN | disclosed |
| CN-1612722-A | Compositions comprising enzymes stabilized with certain osmoprotectants and methods of using such compositions for personal care | PROCTER & GAMBLE (US) | 2005-05-04 | — | — | CN | disclosed |
| WO-2001079349-A1 | UREA MOULDING COMPOUNDS WITH ANTISEPTIC ACTIVITY | PERSTORP CHEMITEC S.P.A. (IT) | 2001-10-25 | — | — | WO | disclosed |