Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31023534 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KMT2ALMNATDP1MAPT | |
| SCHEMBL30255676 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KMT2ALMNATDP1MAPT | |
| SCHEMBL30255431 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KMT2ALMNATDP1MAPT | |
| SCHEMBL31334835 | 0.76 | ALDH1A1 (0.39) | ADAM10ERBB2ALDH1A1LMNAHTR6 | |
| SCHEMBL10036172 | 0.76 | SLC6A4 (0.46) | SLC6A4ADAM10ERBB2ALDH1A1KMT2A | |
| SCHEMBL30736527 | 0.72 | SLC6A4 (0.62) | SLC6A4ALDH1A1KMT2ALMNAHTR6 | |
| SCHEMBL10036370 | 0.72 | SLC6A4 (0.62) | SLC6A4ALDH1A1KMT2ALMNAHTR6 | |
| SCHEMBL31701614 | 0.71 | ALDH1A1 (0.37) | ALDH1A1LMNAMAPT | |
| SCHEMBL10036372 | 0.69 | HTR6 (0.53) | ALDH1A1KMT2AADRA2APNMTCYP3A4 | |
| SCHEMBL31333875 | 0.69 | HTR6 (0.53) | ALDH1A1KMT2AADRA2APNMTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260014147-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2026-01-15 | — | — | US | disclosed |
| US-20250325677-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-23 | — | — | US | disclosed |
| US-20250320205-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-16 | — | — | US | disclosed |
| US-20250320206-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250325677-A1 | STAT6 DEGRADERS | STAT6, STAT5B, STAT1 | SLC6A4 3527/4885ADAM10 851/4885ERBB2 908/4885 |
| US-20250320205-A1 | STAT6 DEGRADERS | STAT6, STAT1, STAT5B | SLC6A4 3929/4885ADAM10 836/4885ERBB2 968/4885 |
| US-20260014147-A1 | STAT6 DEGRADERS | STAT6, NCOR1, CBR1 | SLC6A4 3293/4885ADAM10 2369/4885ERBB2 318/4885 |
| US-20250320206-A1 | STAT6 DEGRADERS | STAT6, STAT5B, STAT1 | SLC6A4 3527/4885ADAM10 851/4885ERBB2 908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.