Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10036406 | 0.88 | SLC6A4 (0.47) | SLC6A4ACHEALDH1A1LMNAHTR1A | |
| SCHEMBL10036370 | 0.84 | SLC6A4 (0.62) | SLC6A4ALDH1A1KMT2ALMNA | |
| SCHEMBL30736527 | 0.84 | SLC6A4 (0.62) | SLC6A4ALDH1A1KMT2ALMNA | |
| SCHEMBL31333879 | 0.81 | CDK9 (0.40) | SLC6A4ALDH1A1KMT2ALMNA | |
| SCHEMBL31333420 | 0.81 | CDK9 (0.40) | SLC6A4ALDH1A1KMT2ALMNA | |
| SCHEMBL31334454 | 0.79 | DRD2 (0.49) | SLC6A4ALDH1A1KMT2AADAM10ERBB2 | |
| SCHEMBL31333302 | 0.77 | DRD2 (0.42) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL14810478 | 0.76 | SLC6A4 (0.45) | SLC6A4ALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL31700717 | 0.76 | SLC6A4 (0.38) | SLC6A4ALDH1A1KMT2ALMNAADAM10 | |
| SCHEMBL3354485 | 0.75 | SLC6A4 (0.47) | SLC6A4ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012053606-A1 | ARYLAMINOHETEROCYCLIC CARBOXAMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-26 | — | — | WO | disclosed |