Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PTGFR | P43088 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30951699 | 0.91 | DNM1 (0.46) | ALOX5LMNAALDH1A1EPHX1DNM1 | |
| SCHEMBL23390635 | 0.88 | ALOX5 (0.44) | ALOX5LMNAALDH1A1EPHX1TBXA2R | |
| SCHEMBL872200 | 0.88 | ALOX5 (0.44) | ALOX5LMNAALDH1A1EPHX1DNM1 | |
| SCHEMBL10084617 | 0.88 | ALOX5 (0.44) | ALOX5LMNAALDH1A1EPHX1DNM1 | |
| SCHEMBL23437455 | 0.88 | ALOX5 (0.44) | ALOX5LMNAALDH1A1EPHX1DNM1 | |
| SCHEMBL23282462 | 0.88 | ALOX5 (0.44) | ALOX5LMNAALDH1A1EPHX1DNM1 | |
| SCHEMBL18657390 | 0.86 | ALOX5 (0.65) | ALOX5LMNAALDH1A1EPHX1DNM1 | |
| SCHEMBL29971764 | 0.86 | ALOX5 (0.65) | ALOX5LMNAALDH1A1EPHX1DNM1 | |
| SCHEMBL18685663 | 0.86 | ALOX5 (0.65) | ALOX5LMNAALDH1A1EPHX1DNM1 | |
| SCHEMBL21935450 | 0.85 | ALOX5 (0.45) | ALOX5LMNAALDH1A1EPHX1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250319188-A1 | ALPHA POLYGLUTAMATED ANTIFOLATES AND USES THEREOF | L E A F HOLDINGS GROUP LLC (US) | 2025-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250319188-A1 | ALPHA POLYGLUTAMATED ANTIFOLATES AND USES THEREOF | FPGS, GGCT, FOLR1 | ALOX5 1559/4885LMNA 4033/4885ALDH1A1 3185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.