SCHEMBL317022

SCHEMBL317022

[CH2]N1C(=O)C=CC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8135505 0.69
SCHEMBL157324 0.67 MGLL (0.50)
SCHEMBL28676621 0.64
SCHEMBL1664700 0.62
SCHEMBL18282001 0.62
SCHEMBL21862009 0.62 MGLL (0.38)
SCHEMBL564245 0.62
SCHEMBL16104380 0.61
SCHEMBL718436 0.61
SCHEMBL19900691 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 428 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022120177-A1 NERVE TARGETING PEPTIDES AND METHODS OF USE ALUME BIOSCIENCES, INC. (US) 2022-06-09 WO claimed
CN-109689107-A Derivatives of amatoxins and their coupling to cell binding molecules 杭州多禧生物科技有限公司 2019-04-26 CN claimed
CN-109437675-A A kind of preparation method of iron oxide skin bit for building 宋洋 2019-03-08 CN claimed
CN-109369853-A A kind of preparation method of cellulose base elastic material 王春华 2019-02-22 CN claimed
CN-107106702-A Method for Synthesizing ADC Using Affinity Resin ADC生物技术公司 2017-08-29 CN claimed
CN-104193825-A Novel IgM-IgG polymer and polymerization method thereof SHANGHAI CHANGDA BIOLOG TECHNOLOGY CO LTD 2014-12-10 CN claimed
EP-1029869-B1 Endothelin converting enzyme inhibitors WELLCOME FOUND (GB) 2003-04-23 EP claimed
US-6235717-B1 Pharmaceutical compounds GLAXO WELLCOME INC. 2001-05-22 US claimed
EP-1029869-A1 Endothelin converting enzyme inhibitors THE WELLCOME FOUNDATION LIMITED (GB) 2000-08-23 EP claimed
EP-0677059-A1 ENDOTHELIN CONVERTING ENZYME INHIBITORS THE WELLCOME FOUNDATION LIMITED (GB) 1995-10-18 EP claimed
WO-1994015956-A1 ENDOTHELIN CONVERTING ENZYME INHIBITORS THE WELLCOME FOUNDATION LIMITED (GB) 1994-07-21 WO claimed
US-4183942-A Insecticidal (β-phenyl-β-substituted-vinyl)cyclopropanecarboxylates FMC CORPORATION (US) 1980-01-15 US claimed
US-4160842-A Insecticidal [β-(substituted-phenyl)vinyl]cyclopropanecarboxylates FMC CORPORATION (US) 1979-07-10 US claimed
US-4157397-A RESISTANT TO PHOTOOXIDATIVE DEGRADATION FMC CORPORATION (US) 1979-06-05 US claimed
US-20240228646-A9 ANTI-TRANSFERRIN RECEPTOR ANTIBODIES AND USES THEREOF AVIDITY BIOSCIENCES INC (US) 2024-07-11 US disclosed
CN-111902148-B Compositions and methods for treating muscular atrophy and tonic muscular dystrophy 艾维迪提生物科学公司 2024-07-05 CN disclosed
CN-118267396-A Nucleic acid-polypeptide compositions and uses thereof 艾维迪提生物科学公司 2024-07-02 CN disclosed
US-4147865-A Benz-(C,D)-indolyl compounds BAYER AKTIENGESELLSCHAFT (DE) 1979-04-03 US disclosed
US-4092300-A ELECTROCOATABLE POLYIMIDE SALT GENERAL ELECTRIC COMPANY (US) 1978-05-30 US disclosed
US-3855180-A CURABLE COMPOSITIONS FROM BLEND OF MALEIMIDO COMPOUND AND VINYL ETHER GEN ELECTRIC 1974-12-17 US disclosed