⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342991 | 0.77 | MGLL (0.62) | — | |
| SCHEMBL114195 | 0.73 | MGLL (0.58) | — | |
| SCHEMBL5826263 | 0.71 | — | — | |
| SCHEMBL1373792 | 0.71 | MGLL (0.76) | — | |
| SCHEMBL1495341 | 0.69 | MGLL (0.77) | — | |
| SCHEMBL29064617 | 0.69 | MGLL (0.77) | — | |
| SCHEMBL88581 | 0.69 | CASP3 (0.48) | — | |
| SCHEMBL14020148 | 0.69 | MGLL (0.46) | — | |
| SCHEMBL7560300 | 0.69 | — | — | |
| SCHEMBL19046582 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107921144-B | Aureostatin analogs and conjugate conjugates thereof with cell-binding molecules | 杭州多禧生物科技有限公司 | 2023-11-28 | — | — | CN | claimed |
| CN-116726190-A | Aureostatin analogs and conjugate conjugates thereof with cell-binding molecules | 杭州多禧生物科技有限公司 | 2023-09-12 | — | — | CN | claimed |
| WO-2023078273-A1 | SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-05-11 | — | — | WO | claimed |
| WO-2023078021-A1 | BCMA MONOCLONAL ANTIBODY AND THE ANTIBODY-DRUG CONJUGATE | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-05-11 | — | — | WO | claimed |
| CN-116077686-A | Enzyme-cleavable Linker and application thereof | 苏州智核生物医药科技有限公司 | 2023-05-09 | — | — | CN | claimed |
| US-20230057350-A1 | A CONJUGATE OF AN AMANITA TOXIN WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-02-23 | — | — | US | claimed |
| WO-2022078524-A4 | SPECIFIC CONJUGATION OF AN ANTIBODY | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2022-12-08 | — | — | WO | claimed |
| CN-115443134-A | Conjugates of cell binding molecules and camptothecin analogs | 杭州多禧生物科技有限公司 | 2022-12-06 | — | — | CN | claimed |
| CN-113717182-B | Naphthoquinone polycyclic derivative, preparation method and application thereof | 西华大学 | 2022-11-29 | — | — | CN | claimed |
| CN-114853642-A | Synthesis method for directly alkylating benzyl position of aromatic compound | 西湖大学 | 2022-08-05 | — | — | CN | claimed |
| EP-2922818-A1 | HYDROPHILIC LINKERS AND THEIR USES FOR CONJUGATION OF DRUGS TO CELL BINDING MOLECULES | Hangzhou Dac Biotech Co., Ltd (CN) | 2015-09-30 | — | — | EP | claimed |
| US-20150250896-A1 | HYDROPHILIC LINKERS AND THEIR USES FOR CONJUGATION OF DRUGS TO A CELL BINDING MOLECULES | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2015-09-10 | — | — | US | claimed |
| WO-2014080251-A1 | HYDROPHILIC LINKERS AND THEIR USES FOR CONJUGATION OF DRUGS TO CELL BINDING MOLECULES | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2014-05-30 | — | — | WO | claimed |
| US-8420802-B2 | Polymer support | UNIVERSITY OF CAPE TOWN (ZA) | 2013-04-16 | — | — | US | claimed |
| EP-2478049-A1 | A POLYMER SUPPORT | University of Cape Town (ZA) | 2012-07-25 | — | — | EP | claimed |
| US-20120178916-A1 | Polymer Support | UNIVERSITY OF CAPE TOWN (ZA) | 2012-07-12 | — | — | US | claimed |
| WO-2011083360-A1 | A POLYMER SUPPORT | UNIVERSITY OF CAPE TOWN (ZA) | 2011-07-14 | — | — | WO | claimed |
| JP-2005517708-A | — | — | 2005-06-16 | — | — | JP | claimed |
| US-20040116702-A1 | Alkoxylated acyl-and bisacylphoshine derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2004-06-17 | — | — | US | claimed |
| WO-2003068783-A1 | ALKOXYLATED ACYL- AND BISACYLPHOSPHINE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-21 | — | — | WO | claimed |