SCHEMBL31703071

SCHEMBL31703071

C[Si](C)(C)CCOCn1c(COC2CCCCO2)c(I)c2cnc(Cl)c(F)c21

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.34
KDM4C Q9H3R0 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31702978 0.81 ALOX5AP (0.33)
SCHEMBL31702968 0.81 L3MBTL1 (0.36) L3MBTL1KDM4CNPC1RAB9A
SCHEMBL31703081 0.71
SCHEMBL31703074 0.70 L3MBTL1 (0.39) L3MBTL1KDM4CNPC1RAB9A
SCHEMBL31702970 0.69
SCHEMBL20154960 0.67 KDM4C (0.35) L3MBTL1KDM4CNPC1RAB9A
SCHEMBL20154953 0.66 NPC1 (0.38) L3MBTL1KDM4CNPC1RAB9A
SCHEMBL20154955 0.63 KDM4C (0.32) KDM4CNPC1RAB9A
SCHEMBL31703037 0.62
SCHEMBL31703050 0.62 L3MBTL1 (0.43) L3MBTL1KDM4CNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025217430-A1 HETEROCYCLIC COMPOUNDS AS NRAS INHIBITORS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-10-16 WO disclosed