Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31703309 | 0.85 | ALDH1A1 (0.74) | KDM4ELMNAKMT2AMEN1TSHR | |
| SCHEMBL31703490 | 0.81 | KDM4E (0.66) | KDM4ELMNAKMT2AMEN1TSHR | |
| SCHEMBL31703451 | 0.81 | ACHE (0.68) | KDM4ELMNAKMT2AMEN1TSHR | |
| SCHEMBL31703255 | 0.78 | KDM4E (0.72) | KDM4ELMNAKMT2AMEN1TSHR | |
| SCHEMBL23495308 | 0.76 | ALDH1A1 (0.81) | KDM4ELMNAKMT2AMEN1HTT | |
| SCHEMBL29436176 | 0.76 | ALDH1A1 (0.81) | KDM4ELMNAKMT2AMEN1HTT | |
| SCHEMBL23495306 | 0.75 | KDM4E (0.58) | KDM4ELMNAKMT2AMEN1TSHR | |
| SCHEMBL29436214 | 0.75 | KDM4E (0.58) | KDM4ELMNAKMT2AMEN1TSHR | |
| SCHEMBL31703155 | 0.75 | MAPT (0.77) | KDM4ELMNAKMT2AMEN1TSHR | |
| SCHEMBL31703482 | 0.75 | KDM4E (0.67) | KDM4ELMNAKMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215121-A1 | HEDGEHOG ACYLTRANSFERASE INHIBITORS | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2025-10-16 | — | — | WO | disclosed |