Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28833830 | 0.80 | ALOX15 (0.43) | HDAC4ALDH1A1NPSR1SMN1; SMN2HPGD | |
| SCHEMBL1718034 | 0.80 | ALOX15 (0.43) | HDAC4ALDH1A1NPSR1SMN1; SMN2HPGD | |
| SCHEMBL1718035 | 0.80 | ALOX15 (0.43) | HDAC4ALDH1A1NPSR1SMN1; SMN2HPGD | |
| SCHEMBL28833784 | 0.80 | ALOX15 (0.43) | HDAC4ALDH1A1NPSR1SMN1; SMN2HPGD | |
| SCHEMBL6635115 | 0.80 | ALOX15 (0.43) | HDAC4ALDH1A1NPSR1SMN1; SMN2HPGD | |
| SCHEMBL1718039 | 0.80 | ALOX15 (0.43) | HDAC4ALDH1A1NPSR1SMN1; SMN2HPGD | |
| SCHEMBL16639029 | 0.74 | HDAC4 (0.71) | HDAC4ALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL6339509 | 0.74 | HDAC4 (0.71) | HDAC4ALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL28833820 | 0.73 | MAPT (0.58) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL28833855 | 0.73 | MAPT (0.58) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215536-A1 | MACROCYCLIC PANRAS INHIBITORS FOR THE TREATMENT OF CANCER | NOVARTIS AG (CH) | 2025-10-16 | — | — | WO | disclosed |